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At lower dose levels (2\u201320 mg Cd per kg per day), fetal development was retarded. Teratogenic effects were not observed and the fetal cadmium concentrations did not differ significantly from the controls, despite the marked cadmium accumulation in the placenta and maternal tissues. The body\u2010weight gain during gestation of all cadmium\u2010treated females was reduced and an absolute weight of adrenals in females given cadmium at doses 4 mg kg<jats:sup>\u22121<\/jats:sup> and higher was significantly increased. The obtained results indicate that cadmium\u2010induced fetal toxicity is associated with concomitant maternal toxicity and alteration in placental function.<\/jats:p>","DOI":"10.1002\/jat.2550020508","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T13:34:50Z","timestamp":1160832890000},"page":"255-259","source":"Crossref","is-referenced-by-count":30,"title":["Teratogenicity, fetal toxicity and tissue concentration of cadmium administered to female rats during organogenesis"],"prefix":"10.1002","volume":"2","author":[{"given":"B.","family":"Bara\u0144ski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Stetkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Trzcinka\u2010ochocka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Sitarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Szymczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000240596"},{"key":"e_1_2_1_3_2","first-page":"429","article-title":"The relationship of cadmium and zinc in experimental teratogenesis","volume":"18","author":"Ferm V. 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