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Conception rate was lowest at the first breeding and lowest in the control group at this time, but in later breedings the conception rates of each group were very similar. No significant differences were noted in litter size, death of fetuses, sex of fetuses and gestational length. Feed consumption was similar in all groups, as were the non\u2010pregnant or pregnant female weight gains. Although the second\u2010generation offspring grew faster than the first\u2010generation offspring, and significantly lower body weights were seen in the 3.0 ppm T\u20102 toxin group at 2, 5 and 6 weeks of age, all offspring reached the normal weight for CD\u20101 mice at 6 weeks of age. Gross and histological evaluation of all animals at postmortem examination did not reveal any significant results, nor were there significant differences in major and minor or retardation defects among the treatment groups. Relative spleen weights of the second\u2010generation offspring were significantly higher in control females compared with the treated groups but treated males had significantly increased relative spleen weights compared with control males of this generation. It was concluded that no long\u2010term reproductive and teratological effects of low\u2010dose dietary T\u20102 toxin were found in this study.<\/jats:p>","DOI":"10.1002\/jat.2550060308","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T14:55:22Z","timestamp":1160837722000},"page":"179-184","source":"Crossref","is-referenced-by-count":10,"title":["Reproductive and teratological effects of continuous low\u2010level dietary T\u20102 toxin in female CD\u20101 mice for two generations"],"prefix":"10.1002","volume":"6","author":[{"given":"C. G.","family":"Rousseaux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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