{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:36:18Z","timestamp":1760574978664,"version":"build-2065373602"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T00:00:00Z","timestamp":1136937600000},"content-version":"vor","delay-in-days":6311,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Applied Toxicology"],"published-print":{"date-parts":[[1988,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rabbits were exposed to aerosols of lithium chloride in metal concentrations of 0.6 and 1.9 mg\/m<jats:sup>3<\/jats:sup> (mass median aerodynamic diameter of 1 \u03bcm) for 4\u20138 weeks, 5 days\/week, 6 h\/day. The lungs were studied by light and electron microscopy, with particular reference to inflammatory changes, structure of alveolar macrophages and alveolar epithelial cells. Macrophages recovered by lung lavage were studied by light and electron microscopy and their oxidative metabolic activity was measured. The content of phospholipids was analysed in lung tissue. Exposure to lithium produced no significant effects. It thus seems that Li<jats:sup>+<\/jats:sup> is less toxic to the lung than the other metals investigated with the same test system, e.g. Ni<jats:sup>2+<\/jats:sup>, Cd<jats:sup>2+<\/jats:sup>, Co<jats:sup>2+<\/jats:sup>, Cr<jats:sup>3+<\/jats:sup> and Cr<jats:sup>6+<\/jats:sup>.<\/jats:p>","DOI":"10.1002\/jat.2550080507","type":"journal-article","created":{"date-parts":[[2006,10,12]],"date-time":"2006-10-12T23:40:03Z","timestamp":1160696403000},"page":"373-375","source":"Crossref","is-referenced-by-count":6,"title":["Rabbit lung after inhalation of lithium chloride"],"prefix":"10.1002","volume":"8","author":[{"given":"Anne","family":"Johansson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Camner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tore","family":"Curstedt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connie","family":"Jarstrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bengt","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Urban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,11]]},"reference":[{"key":"e_1_2_1_2_2","unstructured":"M. D.Hoover F. A.Seiler S. J.RothenbergandR. F.Henderson Studies of lithium aerosols. In Inhalation Toxicology Research Institute Annual Report for 1982\u20101983 pp.46\u201348. Lovelace Biomedial and Environmental Research Institute Albuquerque (1984)."},{"key":"e_1_2_1_3_2","unstructured":"P.Camner M.Casarett\u2010Bruce T.Curstedt C.Jarstrand A.Johansson M.Lundborg B.RobertsonandA.Wiernik Toxicology of nickel. In Proceedings of \u2018Nickel in the Human Environment\u2019 ed. by F. W. Sunderman et al. 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