{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:38:01Z","timestamp":1788446281996,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Applied Toxicology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Sturgeons are particularly vulnerable to the bioaccumulation of trace elements due to their longevity, benthic habits, and slow metabolic turnover. As aquaculture has become the primary global source of caviar, updated information on essential and toxic elements in farmed sturgeon products is needed to assess food safety. Twelve\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Acipenser baerii<\/jats:italic>\n                    <\/jats:styled-content>\n                    at reproductive stage 4 were sampled from a commercial farm in Tehran Province. Caviar was digested using acid\u2010assisted mineralization, and essential (Zn, Cu, Fe, Se) and toxic (Cd, Pb, Cr, As, Hg) elements were quantified. Zinc was the most abundant element (31.0\u201335.9\u2009mg\/kg), while iron (3.0\u20134.9\u2009mg\/kg), copper (0.9\u20131.8\u2009mg\/kg), and selenium (0.38\u20130.64\u2009mg\/kg) fell within expected physiological ranges for farmed sturgeons. Concentrations of toxic elements were consistently low, Cd (0.01\u20130.07\u2009mg\/kg), Pb (0.12\u20130.20\u2009mg\/kg), As (0.07\u20130.15\u2009mg\/kg), Cr (0.14\u20130.31\u2009mg\/kg), and Hg (0.01\u20130.05\u2009mg\/kg), and remained below international safety thresholds. Overall, the trace\u2010element profile of farmed\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>A. baerii<\/jats:italic>\n                    <\/jats:styled-content>\n                    caviar indicates low contaminant levels and compliance with current food\u2010safety standards. These results provide updated baseline information for Iranian sturgeon aquaculture and support the safety of caviar produced under controlled farming conditions.\n                  <\/jats:p>","DOI":"10.1002\/jat.70078","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T06:28:21Z","timestamp":1769495301000},"page":"2865-2871","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bioaccumulation of Trace Metals and Consumer Health Risk Evaluation in Farmed\n                    <scp>\n                      <i>Acipenser baerii<\/i>\n                    <\/scp>\n                    Caviar From Iran"],"prefix":"10.1002","volume":"46","author":[{"given":"Milad","family":"Adel","sequence":"first","affiliation":[{"name":"Department of Aquatic Animal Health and Diseases, Iranian Fisheries Science Research Institute (IFSRI) Agricultural Research Education and Extension Organization (AREEO)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahimeh","family":"Sakhaei","sequence":"additional","affiliation":[{"name":"School of Pharmacy Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Hassanabadi","sequence":"additional","affiliation":[{"name":"Department of Basic Science Islamic Azad University, Central Tehran Branch  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Impellitteri","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Raeisi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science Shahrekord University  Shahrekord Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0066-2421","authenticated-orcid":false,"given":"Caterina","family":"Faggio","sequence":"additional","affiliation":[{"name":"Department of Chemical, Biological, Pharmaceutical and Environmental Sciences University of Messina  Messina Italy"},{"name":"Department of Eco\u2010sustainable Marine Biotechnology Stazione Zoologica Anton Dohrn  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-28862-3.00017-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2023.109321"},{"key":"e_1_2_10_4_1","first-page":"497","article-title":"Liver Accumulation of Trace Elements in Green Turtles (Chelonia mydas) From Coastal Waters of Japan","volume":"49","author":"Agusa T.","year":"2004","journal-title":"Marine Pollution Bulletin"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.167698"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2024.107112"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2022.109761"},{"key":"e_1_2_10_8_1","first-page":"105","article-title":"Bioaccumulation of Copper Nanoparticle in Gill, Liver, Intestine and Muscle of Siberian Sturgeon (Acipenser baerii) Juvenile","author":"Bagherzadeh Lakani F.","year":"2016","journal-title":"Central European Journal of Experimental Biology \u2013 Fisheries & Aquaculture Section"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.116514"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012231526151"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jai.13870"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jai.12628"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconhyd.2024.104399"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpta.2025.100979"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.71027"},{"key":"e_1_2_10_16_1","volume-title":"Osetra Caviar vs Beluga Caviar: Which One Is Better?","author":"Global Seafoods","year":"2024"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.132288"},{"key":"e_1_2_10_18_1","first-page":"976","article-title":"Nnanotoxicity of Silver Nanoparticles to Zebrafish Embryos","volume":"26","author":"Griffitt R. 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