{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:49:23Z","timestamp":1792446563358,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,18]],"date-time":"2014-10-18T00:00:00Z","timestamp":1413590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Polarization\u2010based optical techniques have become increasingly popular in the field of biomedical diagnosis. In the current report we exploit the directional awareness of circularly and\/or elliptically polarized light backscattered from turbid tissue\u2010like scattering media. We apply circularly and elliptically polarized laser light which illuminates the samples of interest, and a standard optical polarimeter is used to observe the polarization state of light backscattered a few millimeters away from the point of incidence. We demonstrate that the Stokes vector of backscattered light depicted on a Poincar\u00e9 sphere can be used to assess a turbid tissue\u2010like scattering medium. By tracking the Stokes vector of the detected light on the Poincar\u00e9 sphere, we investigate the utility of this approach for characterization of cancerous and non\u2010cancerous tissue samples <jats:italic>in vitro<\/jats:italic>. The obtained results are discussed in the framework of a phenomenological model and the results of a polarization tracking Monte Carlo model, developed in house.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:caption><jats:p>Schematic illustration of the experimental approach utilizing circularly and elliptically polarized light for probing turbid tissue\u2010like scattering media.<\/jats:p><\/jats:caption><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/jbio201400104-gra-001-m.png\"><jats:alt-text>magnified image<\/jats:alt-text><jats:caption><jats:p>Schematic illustration of the experimental approach utilizing circularly and elliptically polarized light for probing turbid tissue\u2010like scattering media.<\/jats:p><\/jats:caption><\/jats:graphic><\/jats:boxed-text><\/jats:p>","DOI":"10.1002\/jbio.201400104","type":"journal-article","created":{"date-parts":[[2014,10,18]],"date-time":"2014-10-18T12:58:10Z","timestamp":1413637090000},"page":"317-323","source":"Crossref","is-referenced-by-count":242,"title":["Application of circularly polarized light for non\u2010invasive diagnosis of cancerous tissues and turbid tissue\u2010like scattering media"],"prefix":"10.1002","volume":"8","author":[{"given":"Britt","family":"Kunnen","sequence":"first","affiliation":[{"name":"The Jack Dodd Centre for Quantum Technology, Department of Physics University of Otago  Dunedin 9054 New Zealand"},{"name":"Medical Natural Sciences VU University  Amsterdam The Netherlands"},{"name":"Department of Pathology, Dunedin School of Medicine University of Otago  Dunedin 9054 New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callum","family":"Macdonald","sequence":"additional","affiliation":[{"name":"The Jack Dodd Centre for Quantum Technology, Department of Physics University of Otago  Dunedin 9054 New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Doronin","sequence":"additional","affiliation":[{"name":"The Jack Dodd Centre for Quantum Technology, Department of Physics University of Otago  Dunedin 9054 New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Jacques","sequence":"additional","affiliation":[{"name":"Departments of Biomedical Engineering and Dermatology Oregon Health &amp; Science University  Portland OR 97239\u20103098 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Eccles","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dunedin School of Medicine University of Otago  Dunedin 9054 New Zealand"},{"name":"Maurice Wilkins Centre for Molecular Biodiscovery  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Meglinski","sequence":"additional","affiliation":[{"name":"The Jack Dodd Centre for Quantum Technology, Department of Physics University of Otago  Dunedin 9054 New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,18]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"K.Nouri Skin Cancer (The McGraw\u2010Hill Companies Inc. 2008)."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2011.02798.x"},{"key":"e_1_2_6_4_1","volume-title":"Handbook of Optical Biomedical Diagnostics","author":"Tuchin V. 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