{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:16:51Z","timestamp":1771503411898,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T00:00:00Z","timestamp":1511136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2018,8]]},"abstract":"The commonly used modalities for therapy of limb lymphedema are manual lymphatic drainage, manual devices moving edema fluid and intermittent pneumatic compression (IPC). What seems to be necessary for validation of the effect of the compression procedure is imaging of the mobilized moving edema fluid. Picture of edema fluid flow would allow the therapist to use force adjusted to the tissue volume and stiffness differing in various limb regions as well as identify sites of abundant accumulation of fluid requiring more compression. The purpose of the present study was to visualize tissue edema fluid flow during manual drainage, Linforoll massage, IPC and bandaging. To obtain data how high compression pressures should be used to mobilize indocyanine green (ICG)\u2010stained fluid, concomitantly tissue fluid pressure measurements were performed. The following observations were obtained: (1) the possibility of real\u2010time observation of edema fluid movement using various compression modalities, (2) the threshold pressures necessary to move edema fluid to be over 80 mm Hg in the compression device and over 40 mm Hg in the tissue fluid and (3) inefficacy of compression in some cases despite applying high compression force. These observations point to the need of ICG lymphangiography before compression therapy in each patient. The images observed during the compression procedure give an insight into the distribution of edema fluid, sites of its accumulation and efficacy of applied external force on fluid mobilization.<\/jats:p><\/jats:p>","DOI":"10.1002\/jbio.201700150","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T13:39:20Z","timestamp":1500557960000},"source":"Crossref","is-referenced-by-count":17,"title":["Indocyanine green near\u2010infrared lymphangiography for evaluation of effectiveness of edema fluid flow under therapeutic compression"],"prefix":"10.1002","volume":"11","author":[{"given":"Marzanna T.","family":"Zaleska","sequence":"first","affiliation":[{"name":"Department of Applied Physiology, Mossakowski Medical Research Center Polish Academy of Sciences and Central Clinical Hospital Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waldemar L.","family":"Olszewski","sequence":"additional","affiliation":[{"name":"Department of Applied Physiology, Mossakowski Medical Research Center Polish Academy of Sciences and Central Clinical Hospital Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/978-0-85729-567-5_5","volume-title":"Lymphedema\u2014A Concise Compendium of Theory and Practice","author":"Olszewski W. 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