{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T12:51:41Z","timestamp":1774183901984,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T00:00:00Z","timestamp":1559174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Noninvasive body shaping is becoming a growing demand. The aim of this study was to investigate the efficacy and safety of the combined treatments of 1064\u2009nm Nd:YAG and 2940\u2009nm Er:YAG in noninvasive lipolysis and skin tightening. Ten females were enrolled, and all women's side of the waist or the lower part of the abdomen were treated. In the first step, the 1064\u2009nm Nd:YAG was used. As a second step, the 2940\u2009nm Er:YAG laser was applied. Each woman was treated four times, once every 2 weeks. The effects were determined by comparative photo documentation, waist circumference measurement, two\u2010dimensional B\u2010mode ultrasonography and low\u2010dose native computer tomography (CT), whereas body fat was monitored with bioelectric impedance. The tissue firmness was measured by ultrasound shear wave elastography. Combined laser treatment significantly reduced waist circumference and total body fat. Ultrasonography has revealed that the treatment considerably decreased fat thickness and improved skin stiffness in the treated region. Subcutaneous fat volume, measured by low\u2010dose CT, displayed a moderate decrease in the waist region. The combined 1064\u2009nm Nd:YAG and 2940\u2009nm Er:YAG laser treatment results in the reduction of fat tissue and tightens the skin as confirmed by objective measurements.<\/jats:p><jats:p><jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio201900083-gra-0001.png\" xlink:title=\"image\"\/><\/jats:p>","DOI":"10.1002\/jbio.201900083","type":"journal-article","created":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T11:34:00Z","timestamp":1555932840000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Efficacy and safety of long pulse 1064 and 2940\u2009nm lasers in noninvasive lipolysis and skin tightening"],"prefix":"10.1002","volume":"12","author":[{"given":"Krisztina","family":"Vas","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Besenyi","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szabolcs","family":"Urb\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraf","family":"Badawi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University of Szeged  Szeged Hungary"},{"name":"National Institute of Laser Enhanced Sciences Cairo University  Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"P\u00e1vics","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5945-0370","authenticated-orcid":false,"given":"G\u00e1bor","family":"Er\u0151s","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2119-9501","authenticated-orcid":false,"given":"Lajos","family":"Kem\u00e9ny","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University of Szeged  Szeged Hungary"},{"name":"MTA\u2010SZTE Dermatological Research Group University of Szeged  Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,30]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1","volume":"288","author":"Hales C. 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