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Therefore, phase shift\u2010resolved optical Doppler vibrography (ODV) was used for vibration assessments of moisture influenced cadaveric TM. ODV was applied to generate time resolved cross\u2010sectional and volumetric vibrographs of a cadaveric TM, driven acoustically at several frequencies. In order to analyze the effect of moisture on TM, homogenous moisture conditions were provided by soaking the cadaveric TM specimens in 1\u00d7 phosphate buffer saline with a pH of 7.4. The TM specimen was exposed to a rapidly switchable frequency generator during the ODV image acquisition. The experiment was conducted for 3 hours and the cadaveric TM was exposed to each frequency with an interval of 30\u2009minutes. Acquired phase shift\u2010resolved ODV assessments revealed a depth dependent vibration tendency between the applied frequencies, along with a decline in the moisture level of the cadaveric TM specimen. Thus, the ODV method can aid our understanding of sound conduction in the middle ear, thus supporting the diagnosis of TM diseases.<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio201900202-gra-0001.png\" xlink:title=\"image\"\/><\/jats:p>","DOI":"10.1002\/jbio.201900202","type":"journal-article","created":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T15:09:42Z","timestamp":1572534582000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Functional assessment of moisture influenced cadaveric tympanic membrane using phase shift\u2010resolved optical Doppler vibrography"],"prefix":"10.1002","volume":"13","author":[{"given":"Byeonggyu","family":"Jeon","sequence":"first","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaeyul","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deokmin","family":"Jeon","sequence":"additional","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilun","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, School of Medicine Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Hun","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, School of Medicine Ajou University  Gyeongsan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruchire Eranga","family":"Wijesinghe","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, College of Engineering Kyungil University  Gyeongsan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0630-9039","authenticated-orcid":false,"given":"Mansik","family":"Jeon","sequence":"additional","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeehyun","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2013.06.006"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488809097011"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016486809126286"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-013-0394-z"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2018.12.005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818766320"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2004.00950.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2008.05.010"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182941a95"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.1.001104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.8.000260"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12397"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2017.1416189"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1909444"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.174.2.2296650"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(01)00379-5"},{"key":"e_1_2_7_18_1","first-page":"239","volume":"22","author":"Mafee M.","year":"1993","journal-title":"J. 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