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Our previous studies exploring methods for locating the parathyroid glands using autofluorescence have limitations, such as turning off the surgical light or requiring additional matching between the autofluorescence image and real\u2010surgical field\u2010of\u2010view. We developed a probe\u2010type parathyroid autofluorescence detector using a phase\u2010sensitive process and optical filtering to overcome these limitations. A preliminary clinical trial was performed on eight parathyroid glands in four patients. The normalized mean signal of the normal parathyroid glands was 332% stronger than that of the thyroid, and 384%, 459% and 286% stronger than the signal of the muscle, trachea and fat, respectively. Additionally, the device also detected fluorescence from indocyanine green.<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio201960078-gra-0001.png\" xlink:title=\"image\"\/><\/jats:p>","DOI":"10.1002\/jbio.201960078","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T16:24:12Z","timestamp":1573143852000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Phase\u2010sensitive fluorescence detector for parathyroid glands during thyroidectomy: A preliminary report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2712-7533","authenticated-orcid":false,"given":"Yikeun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering and Center for Marine\u2010Integrated Biomedical Technology Pukyong National University  Busan South Korea"},{"name":"Innovative Biomedical Technology Research Center Pukyong National University\u2010Kosin University  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Innovative Biomedical Technology Research Center Pukyong National University\u2010Kosin University  Busan South Korea"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Kosin University College of Medicine  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Dae","family":"Lee","sequence":"additional","affiliation":[{"name":"Innovative Biomedical Technology Research Center Pukyong National University\u2010Kosin University  Busan South Korea"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Kosin University College of Medicine  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0531-4813","authenticated-orcid":false,"given":"Yeh\u2010Chan","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Center for Marine\u2010Integrated Biomedical Technology Pukyong National University  Busan South Korea"},{"name":"Innovative Biomedical Technology Research Center Pukyong National University\u2010Kosin University  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9384"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9676"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199908000-00010"},{"issue":"11","key":"e_1_2_9_5_1","first-page":"e020788","volume":"13","author":"Binglong B.","year":"2018","journal-title":"PLOS ONE"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-5376-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2018.04.008"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.05.737"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.3583571"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2013.06.046"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2016.04.049"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.06.047"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2017.0102"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2017.09.04"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6364-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.04.079"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-2558"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2017.10.015"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.9.003391"},{"key":"e_1_2_9_20_1","first-page":"e201900017","author":"Kim Yikeun","year":"2019","journal-title":"J. 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