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Recently, endoscopic OCT angiography (OCTA) was successfully achieved in distal scanning systems using an internal\u2010motor\u2010driving catheter. In conventional OCT systems using externally driving catheters, the mechanical instability in the proximal actuation causes difficulties for differentiating capillaries in tissues. In this study, OCTA in an endoscopic OCT system using an external\u2010motor\u2010driving catheter was proposed. Blood vessels were visualized by using a high\u2010stability inter\u2010A\u2010scan scheme and the spatiotemporal singular value decomposition algorithm. It is not limited by nonuniform rotation distortion caused by the catheter and physiological motion artifacts. Results show that microvasculature in a custom\u2010made microfluidic phantom and the submucosal capillaries in the mouse rectum are successfully visualized. Furthermore, OCTA using a catheter with a small size (outer diameter less than 1\u2009mm) makes it possible for early diagnosis of narrow lumens, such as pancreatic and bile duct cancers.<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio202300014-gra-0001.png\" xlink:title=\"image\"\/><\/jats:p>","DOI":"10.1002\/jbio.202300014","type":"journal-article","created":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T16:04:12Z","timestamp":1683993852000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Endoscopic optical coherence tomography angiography using an externally driving catheter"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3973-2693","authenticated-orcid":false,"given":"Lei","family":"Gao","sequence":"first","affiliation":[{"name":"College of Sciences Shanghai Institute of Technology  Shanghai China"},{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengjie","family":"Wu","sequence":"additional","affiliation":[{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoquan","family":"Chen","sequence":"additional","affiliation":[{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiming","family":"Kong","sequence":"additional","affiliation":[{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Song","sequence":"additional","affiliation":[{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Ma","sequence":"additional","affiliation":[{"name":"Country Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuixia","family":"Dai","sequence":"additional","affiliation":[{"name":"College of Sciences Shanghai Institute of Technology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.65"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2020.07.052"},{"key":"e_1_2_9_4_1","volume":"11","author":"Lu L.","year":"2021","journal-title":"Front. 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