{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:53:44Z","timestamp":1790924024033,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T00:00:00Z","timestamp":1687392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T00:00:00Z","timestamp":1687392000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The aim of this study was to develop a clinical SWIR reflectance handpiece to assess the activity of lesions on the occlusal surfaces. The time\u2010resolved reflectivity of 10 active and 10 arrested occlusal caries lesions on extracted teeth was monitored at 1470\u2009nm using a benchtop system and a modified clinical prototype during forced air drying. The presence of a highly mineralized surface layer measured with microcomputed tomography (microCT) was used to indicate lesion activity. Multiple kinetic parameters were extracted from the acquired SWIR time versus intensity dehydration curves and used to assess lesion activity. Three parameters: delay, %\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sub>fin<\/jats:sub>\n                    , and rate calculated from the SWIR dehydration curves were significantly different (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) between active and arrested lesions. The modified clinical probe was able to completely dehydrate all the active lesion areas in the occlusal pits and fissures in less than 30\u2009s.\n                    <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio202300165-gra-0001.png\" xlink:title=\"image\"\/>\n                  <\/jats:p>","DOI":"10.1002\/jbio.202300165","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T22:45:05Z","timestamp":1686782705000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Time\u2010resolved\n                    <scp>SWIR<\/scp>\n                    imaging for the assessment of the activity of occlusal caries lesions"],"prefix":"10.1002","volume":"16","author":[{"given":"Morgan","family":"Ng","sequence":"first","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spencer","family":"Wycoff","sequence":"additional","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihua","family":"Zhu","sequence":"additional","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Ching","family":"Ho","sequence":"additional","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"},{"name":"Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Takasuka","sequence":"additional","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5327-2558","authenticated-orcid":false,"given":"Daniel","family":"Fried","sequence":"additional","affiliation":[{"name":"Preventive and Restorative Dental Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,22]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Dental Caries: The Disease and its Clinical Management","author":"Fejerskov O.","year":"2015"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000260279"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4805177"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22500"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000224213"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.5.002950"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910608500905"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2015.03.005"},{"key":"e_1_2_9_10_1","volume":"22","author":"Lee R. 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