{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:32:43Z","timestamp":1792085563450,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T00:00:00Z","timestamp":1689033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T00:00:00Z","timestamp":1689033600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To evaluate the efficacy of photodynamic therapy (PDT) as adjunctive to oral debridement (OD) in the improvement of clinical, microbiological, and pain in patients with necrotizing ulcerative gingivitis (NUG). Patients with NUG were split into two groups: Group\u2010OD\u2009+\u2009PDT received PDT with OD, while Group\u2010OD underwent OD alone. Clinical inflammatory parameters including full mouth plaque scores (FMPS), full mouth bleeding scores (FMBS), and probing depth (PD) were assessed.\n                    <jats:italic>Fusobacterium nucleatum<\/jats:italic>\n                    and\n                    <jats:italic>Prevotella intermedia<\/jats:italic>\n                    were analyzed using the polymerase chain reaction technique. Pain examination was done using various pain scales. Group PDT\u2009+\u2009OD showed more reduction in FMPS, FMBS, and greater reduction in\n                    <jats:italic>F. nucleatum<\/jats:italic>\n                    and\n                    <jats:italic>P. intermedia<\/jats:italic>\n                    count compared to group OD at 12\u2009weeks follow up (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01). Group PDT\u2009+\u2009OD showed significantly lower pain scores at 12\u2009weeks (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). PDT was more effective in improving clinical parameters, and reducing bacterial counts and pain in NUG patients than dental scaling alone.\n                    <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jbio202300197-gra-0001.png\" xlink:title=\"image\"\/>\n                  <\/jats:p>","DOI":"10.1002\/jbio.202300197","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T22:10:46Z","timestamp":1687903846000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effectiveness of photodynamic therapy adjunct to oral debridement in improving clinical, microbiological, and pain in necrotizing ulcerative gingivitis"],"prefix":"10.1002","volume":"16","author":[{"given":"Abdulaziz A.","family":"Al\u2010Kheraif","sequence":"first","affiliation":[{"name":"Dental Health Department, College of Applied Medical Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravish","family":"Javed","sequence":"additional","affiliation":[{"name":"Biomedical Technology Department, College of Applied Medical Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Mahmoud","family":"Al\u2010Momani","sequence":"additional","affiliation":[{"name":"Community Health Sciences Department, College of Applied Medical Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisha","family":"Wasi","sequence":"additional","affiliation":[{"name":"Dental Health Department, College of Applied Medical Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aftab Ahmed","family":"Khan","sequence":"additional","affiliation":[{"name":"Dental Health Department, College of Applied Medical Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,11]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"65","volume":"2020","author":"Ryder M. 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