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A pilot study was carried out using a novel optical coherence elastography (OCE) device, combining mechanical characterization through suction\u2010based deformation and imaging through optical coherence tomography. Using AI\u2010assisted image segmentation and a power\u2010law model, we were able to describe the mechanical behavior, comparing with measurements from the most commonly used commercial instrument (Cutometer) and subjective analyses of stiffness using the Patient and Observer Scar Assessment Scale. Twenty subjects were included with either keloids or hypertrophic scars. Measurements were fast and produced no discomfort. Mechanical and structural (epidermal thickness and rugosity) descriptors in pathologic skin conditions differed significantly from those in control tissue. 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