{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T15:46:17Z","timestamp":1782488777910,"version":"3.54.5"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cystic echinococcosis (CE) is a grievous zoonotic parasitic disease. Currently, the traditional technology of screening CE is laborious and expensive, developing an innovative technology is urgent. In this study, we combined serum fluorescence spectroscopy with machine learning algorithms to develop an innovative screening technique to diagnose CE in sheep. Serum fluorescence spectra of <jats:italic>Echinococcus granulosus<\/jats:italic> sensu stricto\u2010infected group (<jats:italic>n<\/jats:italic>\u2009=\u200963) and uninfected <jats:italic>E. granulosus s.s.<\/jats:italic> group (<jats:italic>n<\/jats:italic>\u2009=\u200960) under excitation at 405\u2009nm were recorded. The linear support vector machine (Linear SVM), Quadratic SVM, medium radial basis function (RBF) SVM, K\u2010nearest neighbor (KNN), and principal component analysis\u2010linear discriminant analysis (PCA\u2010LDA) were used to analyze the spectra data. The results showed that Quadratic SVM had the great classification capacity, its sensitivity, specificity, and accuracy were 85.0%, 93.8%, and 88.9%, respectively. In short, serum fluorescence spectroscopy combined with Quadratic SVM algorithm has great potential in the innovative diagnosis of CE in sheep.<\/jats:p>","DOI":"10.1002\/jbio.202300357","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T04:10:30Z","timestamp":1706069430000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Rapid and non\u2010invasive detection of cystic echinococcosis in sheep based on serum fluorescence spectrum combined with machine learning algorithms"],"prefix":"10.1002","volume":"17","author":[{"given":"Shengke","family":"Xu","sequence":"first","affiliation":[{"name":"College of Life Sciences and Technology, Xinjiang University  Urumqi Xinjiang China"},{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"},{"name":"Xinjiang Key Laboratory of Echinococcosis The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wubulitalifu","family":"Dawuti","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"},{"name":"Department of Epidemiology and Biostatistics School of Public Health, Peking University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maierhaba","family":"Maimaitiaili","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"},{"name":"Xinjiang Key Laboratory of Echinococcosis The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrui","family":"Dou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malike","family":"Aizezi","sequence":"additional","affiliation":[{"name":"Animal Health Supervision Institute of Xinjiang Uygur Autonomous Region  Urumqi Xinjiang PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalibixiati","family":"Aimulajiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"},{"name":"Xinjiang Key Laboratory of Echinococcosis The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"L\u00fc","sequence":"additional","affiliation":[{"name":"College of Software, Xinjiang University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1770-574X","authenticated-orcid":false,"given":"Guodong","family":"L\u00fc","sequence":"additional","affiliation":[{"name":"College of Life Sciences and Technology, Xinjiang University  Urumqi Xinjiang China"},{"name":"State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"},{"name":"Xinjiang Key Laboratory of Echinococcosis The First Affiliated Hospital of Xinjiang Medical University  Urumqi Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00075-18"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-020-00747-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30466-3"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0000235"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-017-2545-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-017-0374-3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12649"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.07.028"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8859116"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202200320"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2019.57.1.61"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737159.2015.1036744"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-011-0958-4"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02673-5"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma13092105"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2021.102276"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2017.03.014"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1088\/1054-660X\/24\/1\/015701"},{"key":"e_1_2_10_20_1","volume":"16","author":"Dou J.","year":"2023","journal-title":"J. Biol. Photonics"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/s19235298"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2019.101598"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2018.05.012"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2019.02.018"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja507848f"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160709300609"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.7785\/tcrt.2012.500282"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2021.101456"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11020061"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00541"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2022.112598"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10053-6"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2014.03.009"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202200354"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.3390\/s21144623"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1039\/b922045c"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2022.102811"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1109\/TCYB.2019.2951811"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00500-017-2751-z"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/app12115345"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2023.124457"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucom.2017.04.018"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2021.120684"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.05.029"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1562\/0031-8655(2003)0780197NFSOBP2.0.CO2"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijleo.2020.165446"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.10.004999"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.17.9.098001"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10479-022-04655-x"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2021.3137605"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejor.2020.10.040"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2022.121654"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.0c01046"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26113400"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1228"},{"key":"e_1_2_10_56_1","first-page":"1","volume-title":"Electric, Electronics, Computer Science, Biomedical Engineerings' Meeting (EBBT),","author":"Ek\u0131z S.","year":"2017"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2017.06.015"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.30539\/iraqijvm.v35i1.599"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1097897"}],"container-title":["Journal of Biophotonics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.202300357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T03:46:25Z","timestamp":1712807185000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbio.202300357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,23]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/jbio.202300357"],"URL":"https:\/\/doi.org\/10.1002\/jbio.202300357","archive":["Portico"],"relation":{},"ISSN":["1864-063X","1864-0648"],"issn-type":[{"value":"1864-063X","type":"print"},{"value":"1864-0648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,23]]},"assertion":[{"value":"2023-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202300357"}}