{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:55:55Z","timestamp":1753869355726,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the effectiveness of the REFIX technology in the remineralization process of initial caries simulated on bovine enamel. The assessment involved the analysis of backscatter intensity, which was determined from laser speckle images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010one bovine teeth were divided into three groups: G1 and G7 were submitted to treatment with the REFIX technology for 1 and 7\u2009days, respectively. The control group was treated with deionized water.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant difference in backscatter was found between the carious and sound areas in all groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.0038, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001, and <jats:italic>p<\/jats:italic>\u2009=\u20090.0002 for the control group, G1, and G7, respectively). The intergroup comparison revealed no significant difference among the groups studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>REFIX technology did not alter the optical properties of the samples of bovine teeth with simulated initial caries lesions after 1 and 7\u2009days of treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jbio.202400144","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T09:39:16Z","timestamp":1725269956000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of <scp>REFIX<\/scp> Technology on the Remineralization of Artificial Early Enamel Caries Lesion by Laser Speckle Tracking Analysis"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7825-6725","authenticated-orcid":false,"given":"Amanda\u00a0Rafaelly\u00a0Hon\u00f3rio","family":"Mandetta","sequence":"first","affiliation":[{"name":"Postgraduation Program in Biophotonic Medicine Universidade Nove de Julho\u2014UNINOVE  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3778-7444","authenticated-orcid":false,"given":"Maria\u00a0Aparecida\u00a0de\u00a0Andrade\u00a0Moreira","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Orthodontics and Public Health Dental School of Bauru, USP\u2014Universidade de S\u00e3o Paulo  Bauru SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5740-2586","authenticated-orcid":false,"given":"Patr\u00edcia\u00a0Bella","family":"Costa","sequence":"additional","affiliation":[{"name":"Coordinator of the Postgraduate Course in Dentistry at Faculdade S\u00e3o Leopoldo Mandic, SP Unit SP  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1084-9940","authenticated-orcid":false,"given":"Elaine\u00a0Marc\u00edlio","family":"Santos","sequence":"additional","affiliation":[{"name":"Postgraduation Program in Health and Environment Universidade Metropolitana de Santos\u2014UNIMES  Santos SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1305-5257","authenticated-orcid":false,"given":"Marcela\u00a0Let\u00edcia","family":"Leal\u00a0Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Postgraduation Program 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