{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T06:31:04Z","timestamp":1780641064419,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We evaluated the effect of infrared thermography (IRT) on the clinical assessment of bacterial and viral pharyngitis and its impact on the predictive value of the McIsaac score algorithm for streptococcal pharyngitis in children. We also investigated if IRT could distinguish between bacterial and viral pharyngitis. The study included children aged 2\u201317 years presenting with sore throat and fever over 38\u00b0C from November 1, 2021, to April 30, 2022. Of the 76 assessed children, 16 were excluded due to missing data or technical issues, leaving 60 children (32 males, 28 females) divided into three groups: Group A with streptococcal pharyngitis (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200930), viral pharyngitis (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200916), and healthy controls (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200914). McIsaac score and IRT imaging showed a 90% positive predictive value for streptococcal pharyngitis. While IRT alone could not distinguish between bacterial and viral infections, it significantly increased the predictive value when combined with the McIsaac score.\n                  <\/jats:p>","DOI":"10.1002\/jbio.202400219","type":"journal-article","created":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T22:53:28Z","timestamp":1728860008000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Novel Diagnostic Approach for Acute Pharyngitis: Combining Machine Learning With Thermal Imaging"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6570-3300","authenticated-orcid":false,"given":"Oshrit","family":"Hoffer","sequence":"first","affiliation":[{"name":"School of Electrical Engineering Afeka Tel Aviv, Academic College of Engineering  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moriya","family":"Cohen","sequence":"additional","affiliation":[{"name":"Statistics Department Ariel University  Ariel Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Gerstein","sequence":"additional","affiliation":[{"name":"Statistics Department Ariel University  Ariel Israel"},{"name":"Pediatric Ambulatory Community Clinic  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vered","family":"Shkalim Zemer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tel Aviv University  Tel Aviv Israel"},{"name":"Dan\u2010Petach Tikva District, Clalit Health Services  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Reichenberg","sequence":"additional","affiliation":[{"name":"Dan\u2010Petach Tikva District, Clalit Health Services  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dima","family":"Bykhovsky","sequence":"additional","affiliation":[{"name":"Electrical and Electronics Engineering Department Shamoon College of Engineering  Be'er\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshe","family":"Hoshen","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics Jerusalem College of Technology  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman Avner","family":"Cohen","sequence":"additional","affiliation":[{"name":"Pediatric Ambulatory Community Clinic  Petah Tikva Israel"},{"name":"Dan\u2010Petach Tikva District, Clalit Health Services  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-05211-w"},{"key":"e_1_2_11_3_1","first-page":"251","article-title":"Pharyngitis: Approach to Diagnosis and Treatment","volume":"66","author":"Sykes E. A.","year":"2020","journal-title":"Canadian Family Physician"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis629"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-019-0696-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.563627"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01494-19"},{"key":"e_1_2_11_8_1","first-page":"500","article-title":"Antibiotic Stewardship for Community\u2010Acquired Pediatric Pharyngitis: A Pre\u2010Post Intervention Study","volume":"25","author":"Machnes M. D.","year":"2023","journal-title":"Israel Medical Association Journal"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/524891"},{"key":"e_1_2_11_10_1","first-page":"668","volume-title":"Red Book 2012: Report of the Committee on Infectious Diseases","author":"American Academy of Pediatrics","year":"2012"},{"key":"e_1_2_11_11_1","unstructured":"Israeli Pediatric Association \u201cGroup A Streptococcus in Children (GAS) Clinical Guidelines \u201daccessed March 15 2024 https:\/\/www.ima.org.il\/userfiles\/image\/clinical_88_DaleketLoaHada.pdf."},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000100577.76542.af"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2017-000080"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202300486"},{"issue":"1","key":"e_1_2_11_15_1","first-page":"A83.2\u2010A83","article-title":"Thermal Profiling of Cervical Carcinoma Patients Undergoing Brachytherapy: A Novel Diagnostic Approach","volume":"34","author":"Rabin T.","year":"2024","journal-title":"International Journal of Gynecological Cancer"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202200214"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-33556-7"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.36740\/10.36740\/WLek202003101"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.12669\/pjms.332.12167"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X8100100304"},{"key":"e_1_2_11_21_1","first-page":"75","article-title":"A Clinical Score to Reduce Unnecessary Antibiotic Use in Patients With Sore Throat","volume":"158","author":"McIsaac W. J.","year":"1998","journal-title":"Canadian Medical Association Journal"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-003943"},{"issue":"1","key":"e_1_2_11_23_1","first-page":"1","article-title":"Guideline for the Management of Acute Sore Throat","volume":"18","author":"ESCMID Sore Throat Guideline Group","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.13.1374"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2018.12.005"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmw014"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001482"},{"issue":"5","key":"e_1_2_11_28_1","first-page":"299","article-title":"Machine Learning for Clinical Decision Support of Acute Streptococcal Pharyngitis: A Pilot Study","volume":"26","author":"Hoffer O.","year":"2024","journal-title":"Israel Medical Association Journal"},{"key":"e_1_2_11_29_1","first-page":"353","article-title":"Antibiotic Overuse and Its Effects on Our Planet","volume":"24","author":"Ashkenazi S.","year":"2022","journal-title":"Israel Medical Association Journal"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg9868"}],"container-title":["Journal of Biophotonics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.202400219","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbio.202400219","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.202400219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T02:56:03Z","timestamp":1773024963000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbio.202400219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,13]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/jbio.202400219"],"URL":"https:\/\/doi.org\/10.1002\/jbio.202400219","archive":["Portico"],"relation":{},"ISSN":["1864-063X","1864-0648"],"issn-type":[{"value":"1864-063X","type":"print"},{"value":"1864-0648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,13]]},"assertion":[{"value":"2024-05-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202400219"}}