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This study integrates upper limb multimodal tasks (ULMTs) with functional near\u2010infrared spectroscopy (fNIRS) to assess cognitive and motor functions in MCI patients. Thirty\u2010seven elderly participants were categorized into healthy control (HC) and MCI groups. The experiment consisted of resting state, numerical cognitive task (NCT), motor task (MT), and ULMT phases. fNIRS measured hemodynamic responses in the prefrontal and motor cortices, while an upper limb trainer recorded motor data. Results showed weaker cortical responses in the MCI group during rest and reduced motor cortex activation during NCT. Both groups displayed increased cortical activity during ULMT compared to NCT but reduced motor performance compared to MT. These findings demonstrate the potential of ULMTs combined with fNIRS for early MCI assessment and intervention.<\/jats:p>","DOI":"10.1002\/jbio.202500020","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:09:36Z","timestamp":1747192176000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Application of Upper Limb Multimodal Tasks Combined With <scp>fNIRS<\/scp> Technology in the Assessment of Mild Cognitive Impairment"],"prefix":"10.1002","volume":"18","author":[{"given":"Zhenda","family":"You","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering Hebei University of Technology  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Laboratory of Robotics Mechanism and Cross Innovation, School of Intelligent Engineering and Automation Beijing University of Posts and Telecommunications  Beijing China"},{"name":"Beijing Key Laboratory of Rehabilitation Technical Aids for Old\u2010Age Disability, National Research Center for Rehabilitation Technical Aids  Beijing China"},{"name":"Key Laboratory of Neuro\u2010Functional Information and Rehabilitation Engineering of the Ministry of Civil Affairs  Beijing P. 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