{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:40:34Z","timestamp":1781052034815,"version":"3.54.1"},"reference-count":82,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a universal technique for noninvasive investigation of thin multilayer optically transparent tissues based on polarization\u2010sensitive optical coherence tomography. To reach higher diagnostic accuracy, we revisit the model of the cornea structure and reconsider the physical features of the interaction of light with the tissue structural elements. In the scheme proposed, the probing beam is algorithmically adjustable such that the <jats:italic>x<\/jats:italic>\u2010polarized radiation impinges each consecutive structural layer; the object beam is formed by the reflection and back\u2010scattering. Its characteristics are found analytically and numerically within the framework of the polarized Monte\u2010Carlo model and the Jones matrix formalism. A modified Mach\u2013Zehnder interferometer with orthogonal polarization channels enables the elimination of the object\u2010signal depolarization caused by stochastic scattering and facilitates evaluation of the refractive indices and birefringence of tissue elements. The technique permits spatial scanning of the object, providing a complete 3D mapping with a submicrometer resolution in the longitudinal and transverse directions.<\/jats:p>","DOI":"10.1002\/jbio.202500101","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T22:06:02Z","timestamp":1750802762000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comprehensive Investigation of the Eye\u2010Cornea Structure Based on the Extended Techniques of Polarization\u2010Sensitive Optical Coherence Tomography"],"prefix":"10.1002","volume":"18","author":[{"given":"O. V.","family":"Angelsky","sequence":"first","affiliation":[{"name":"Taizhou Institute of Zhejiang University  Taizhou Zhejiang China"},{"name":"Chernivtsi National University  Chernivtsi Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4153-559X","authenticated-orcid":false,"given":"A. Y.","family":"Bekshaev","sequence":"additional","affiliation":[{"name":"Physics Research Institute Odesa I. I. Mechnikov National University  Odesa Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Yu.","family":"Zenkova","sequence":"additional","affiliation":[{"name":"Taizhou Institute of Zhejiang University  Taizhou Zhejiang China"},{"name":"Chernivtsi National University  Chernivtsi Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. I.","family":"Ivanskyi","sequence":"additional","affiliation":[{"name":"Chernivtsi National University  Chernivtsi Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Zheng","sequence":"additional","affiliation":[{"name":"Taizhou Institute of Zhejiang University  Taizhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"The MOE Key Laboratory of Weak\u2010Light Nonlinear Photonics and International Sino\u2010Slovenian Join Research Center on Liquid Crystal Photonics, TEDA Institute of Applied Physics and School of Physics Nankai University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu.","family":"Ursuliak","sequence":"additional","affiliation":[{"name":"Municipal Enterprise Chernivtsi Regional Clinical Cardiological Center  Chernivtsi Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-06419-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.2.025003"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/49\/7\/011"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphy.2021.744346"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-27410-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphy.2022.1060787"},{"issue":"5","key":"e_1_2_8_8_1","first-page":"217","article-title":"Mechanical Action of the Transverse Spin Momentum of an Evanescent Wave on Gold Nanoparticles in Biological Objects Media","volume":"20","author":"Angelsky O. V.","year":"2018","journal-title":"Journal of Optoelectronics and Advanced Materials"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1998.tb05165.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2011.06.003"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.1483879"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-06419-2"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphy.2023.1260830"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.15330\/pcss.24.4.729-734"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1117\/12.3009121"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1364\/OPEX.13.005739"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw179"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13150"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-3669"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10194490"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_646_17"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22249699"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.41.001981"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000003172"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4387"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.23.021043"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.7.002650"},{"key":"e_1_2_8_28_1","volume-title":"A Practical Guide to Optical Metrology for Thin Films","author":"Quinten M.","year":"2013"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713688609029242"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1366\/13-07395"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.80.627"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1109\/2944.796325"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1101-1245"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC01445J"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201600314"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201500273"},{"key":"e_1_2_8_37_1","volume-title":"Light Scattering by Small Particles","author":"Hulst H. C.","year":"1957"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.21037\/qims-20-1052"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1117\/3.1003040"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1364\/OPEX.13.004420"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1364\/AO.55.002681"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1364\/AO.42.003290"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.1483315"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.17.016590"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1364\/AO.53.007576"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1364\/AO.53.007586"},{"issue":"6","key":"e_1_2_8_47_1","first-page":"886","article-title":"Monte Carlo Modeling of Polarized Light Propagation in Biological Tissues","volume":"14","author":"Gangnus S. V.","year":"2004","journal-title":"Laser Physics"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAA.31.002394"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.17.11.115001"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/0169-2607(95)01640-F"},{"key":"e_1_2_8_51_1","unstructured":"\u201cWolfram Mathematica \u201d(Wolfram Research) https:\/\/www.wolfram.com\/mathematica\/."},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527618156"},{"key":"e_1_2_8_53_1","volume-title":"Optics","author":"Hecht E.","year":"2017"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3182504346"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5657"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-15348"},{"issue":"5","key":"e_1_2_8_57_1","article-title":"Human Stromal Lamellar Morphology and Its Relationship to Central to Peripheral Thickness Change","volume":"57","author":"Bergmanson J. P. G.","year":"2016","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2014.0717"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOT.77.000577"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAA.12.001425"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78784-8"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1054\/tice.2001.0195"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4835(03)00208-2"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2015.08.046"},{"issue":"3","key":"e_1_2_8_65_1","first-page":"459","article-title":"Effect of Corneal Light Scatter on Vision: A Review of the Literature","volume":"9","author":"Spadea L.","year":"2016","journal-title":"International Journal of Ophthalmology"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.2.002905"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1364\/OPEX.13.002182"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.22.005325"},{"key":"e_1_2_8_69_1","unstructured":"\u201cIEDM 2023 Conference Handout \u201dhttps:\/\/iedm23.mapyourshow.com\/mys_shared\/iedm23\/handouts\/40\u20101_Wed_12832.pdf."},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep09654"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.42.002667"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.37.003102"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.8.001221"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-19950301-09"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-16638-0_3"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.18.021714"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.33.001581"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1117\/3.626141"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.7.071114"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAA.28.000475"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1117\/12.3014299"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.37190\/oa240302"},{"issue":"4","key":"e_1_2_8_83_1","first-page":"485","article-title":"Discrete Hilbert Transform: Numeric Algorithms","volume":"49","author":"Todoran G.","year":"2008","journal-title":"Acta Electrotehnica et Informatica"}],"container-title":["Journal of Biophotonics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.202500101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T23:22:57Z","timestamp":1759965777000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbio.202500101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,24]]},"references-count":82,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/jbio.202500101"],"URL":"https:\/\/doi.org\/10.1002\/jbio.202500101","archive":["Portico"],"relation":{},"ISSN":["1864-063X","1864-0648"],"issn-type":[{"value":"1864-063X","type":"print"},{"value":"1864-0648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,24]]},"assertion":[{"value":"2025-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202500101"}}