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The approach to create a spatial map of tissue oxygen saturation (StO<jats:sub>2<\/jats:sub>) and total hemoglobin concentration (<jats:italic>C<\/jats:italic>\n<jats:sub>HbT<\/jats:sub>) is based on a multiple regression model using Monte Carlo simulation of light transport in tissues to specify relationships between RGB values, oxygenated hemoglobin concentration, and deoxygenated hemoglobin concentration. Experiments with an optical phantom are performed to confirm the ability of the approach to detect changes in StO<jats:sub>2<\/jats:sub> and <jats:italic>C<\/jats:italic>\n<jats:sub>HbT<\/jats:sub> under different working distances of the endoscope that may occur during actual surgery. In\u00a0vivo experiments in rats confirm that the proposed approach can quantitatively monitor changes in StO<jats:sub>2<\/jats:sub> and <jats:italic>C<\/jats:italic>\n<jats:sub>HbT<\/jats:sub> induced in the small intestine, liver, and cecum. The proposed approach has the potential as a tool for monitoring intraperitoneal organs in real time during laparoscopy.<\/jats:p>","DOI":"10.1002\/jbio.70030","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:51:43Z","timestamp":1744163503000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>RGB<\/scp>\u2010Image\u2010Based Real\u2010Time Hemodynamic Monitoring of Intraperitoneal Organs in Rats Using a Standard Laparoscopic Imaging System"],"prefix":"10.1002","volume":"18","author":[{"given":"Rokeya","family":"Khatun","sequence":"first","affiliation":[{"name":"Graduate School of Bio\u2010Applications &amp; Systems Engineering Tokyo University of Agriculture and Technology  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurika","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Graduate School of Bio\u2010Applications &amp; Systems Engineering Tokyo University of Agriculture and Technology  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koyuki","family":"Kashiwagi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Tokyo University of Agriculture and Technology  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Nagahama","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Tokyo University of Agriculture and Technology  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Division of Oral &amp; Medical Management, Department of Medicine Fukuoka Dental College, Section of General Surgery  Fukuoka Fukuoka Japan"},{"name":"Division of Oral &amp; Medical Management, Center of Endoscopy, Endoscopic Therapy and Surgery Fukuoka Dental College, Section of General Surgery  Fukuoka Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Nagahara","sequence":"additional","affiliation":[{"name":"Osaka University, Institute for Datability Science  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9263-6334","authenticated-orcid":false,"given":"Izumi","family":"Nishidate","sequence":"additional","affiliation":[{"name":"Graduate School of Bio\u2010Applications &amp; Systems Engineering Tokyo University of Agriculture and Technology  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.09.036"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.02.044"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464\u2010410X.2012.11490.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.5194\/jsss\u20105\u2010313\u20102016"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.10.106006"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.6.004179"},{"key":"e_1_2_11_8_1","unstructured":"S. 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