{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:01:23Z","timestamp":1781586083327,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Photobiomodulation (PBM) therapy is widely investigated for tissue recovery, performance enhancement, and post\u2010exercise optimization. This study assessed whether PBM applied to the vagus nerve in the infra\u2010auricular region, combined with resistance exercise, modulates cardiac autonomic function in healthy, physically active adults. In this acute randomized controlled trial, 34 volunteers were enrolled: 17 underwent PBM or sham PBM in a crossover design, while a control group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200917) received PBM without exercise. PBM was delivered with a total energy dose of 12\u2009J. Heart rate variability (HRV) was analyzed in time, frequency, and non\u2010linear domains. Results showed a slight reduction (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.011) in approximate entropy (ApEn) in the PBM group compared with controls, but no significant differences were observed in other HRV indices. These findings suggest that PBM applied to the vagus nerve induces minimal acute modulation of autonomic complexity. Further studies with different dosimetries and exercise protocols are warranted.\n                  <\/jats:p>","DOI":"10.1002\/jbio.70242","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:29:36Z","timestamp":1773221376000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Acute Photobiomodulation on Heart Rate Variability in Physically Active Individuals: A Randomized and Controlled Clinical Trial"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2578-2611","authenticated-orcid":false,"given":"Reobbe Aguiar","family":"Pereira","sequence":"first","affiliation":[{"name":"Post\u2010Graduation Program in Biomedical Engineering University Brazil  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4837-3936","authenticated-orcid":false,"given":"Aparecida 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