{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:04:23Z","timestamp":1784192663258,"version":"3.55.0"},"reference-count":65,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Approximately 80% of the world population has had, has, or will have back pain. The aim of this study is to investigate the acute and chronic effects of the synergistic application of photobiomodulation with mechanical systems on low back pain. Patients with low back pain were randomly distributed into 5 groups: 1\u2010 Vacuum therapy combined with Laser (VL); 2\u2010 Roller combined with Laser (RL); 3\u2010 Ultrasound combined with Laser (USL); 4\u2010 Punctual Laser (L); and 5\u2010 Placebo Laser (P). All treatments were performed in the posterior region of the trunk (lumbar, thoracic, and cervical), totaling 20\u2009min, once a week for 7 sessions. Pain assessment, biomechanical measurement, kinesiological evaluation, and questionnaires to assess quality of life and well\u2010being were performed. There were pain reduction and increased isometric strength, flexibility, and mobility, improving some aspects of life quality and well\u2010being, especially when combined therapies were applied for rehabilitation of back pain.<\/jats:p>","DOI":"10.1002\/jbio.70299","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:23:24Z","timestamp":1779967404000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Photobiomodulation by Laser and Mechanical Systems on Low Back Pain: A Longitudinal, Randomized, Placebo\u2010Controlled Clinical Trial"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9959-3269","authenticated-orcid":false,"given":"Adriana Teresa Silva","family":"Santos","sequence":"first","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences Federal University of Alfenas (UNIFAL)  Alfenas State of Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1255-8429","authenticated-orcid":false,"given":"Andreia Maria Silva Vilela","family":"Terra","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences Federal University of Alfenas (UNIFAL)  Alfenas State of Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1774-9053","authenticated-orcid":false,"given":"Nivaldo Antonio","family":"Parizotto","sequence":"additional","affiliation":[{"name":"Research and Development Institute \u2010 Biomedical Engineering Program University Brasil \u2010 Rua Carolina Fonseca  S\u00e3o Paulo State of S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4833-239X","authenticated-orcid":false,"given":"Vanderlei Salvador","family":"Bagnato","sequence":"additional","affiliation":[{"name":"Optics Group From S\u00e3o Carlos Institute of Physics (IFSC) University of S\u00e3o Paulo  S\u00e3o Carlos State of S\u00e3o Paulo Brazil"},{"name":"Department of Biomedical Engineering Texas A&amp;M University, CPRIT Scholar in Cancer Research  College Station Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1700-3852","authenticated-orcid":false,"given":"Fernanda Rossi","family":"Paolillo","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences Federal University of Alfenas (UNIFAL)  Alfenas State of Minas Gerais Brazil"},{"name":"Group of Technology Applied to Health and Motricity Sciences From State University of Minas Gerais (UEMG)  Passos State of Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization (WHO) \u201cLow Back Pain \u201daccessed September 2025 https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/low\u2010back\u2010pain."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32279-7"},{"key":"e_1_2_10_4_1","unstructured":"Sociedade Brasileira Para Estudo Da Dor (SBED) \u201cLombalgia \u201daccessed at May 2025 https:\/\/www.sbed.org\/lermais_materias.php?cd_materias=541&friurl=_\u2010Lombalgia\u2010_."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.12.010"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00393-7"},{"key":"e_1_2_10_7_1","unstructured":"Sociedade Brasileira Para Estudo Da Dor (SBED) \u201cDor no Brasil \u201daccessed at September 2025 https:\/\/www.sbed.org\/materias.php?cd_secao=74."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001939"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afac220"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.53807"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2024.11.032"},{"key":"e_1_2_10_12_1","first-page":"1","article-title":"Can a New Synergistic Proposal Involving Photobiomodulation and Myofascial Release Accelerate the Evolution of Adhesive Capsulitis and Tendinopathies?","volume":"12","author":"Canelada A. 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