{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:56:20Z","timestamp":1790556980118,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This paper investigates the effect of process parameters and chitosan\u2010based precoating on mechanical properties and thermal damage during laser repair of esophageal tissue. The effects of laser power, defocusing amount, and concentrations of indocyanine green (ICG) and carbon nanotubes (CNT) on burst pressure strength, thermal denaturation degree, and microstructure characteristic parameters were investigated. To maximize burst pressure strength and minimize thermal damage, response surface models were constructed to correlate process parameters with burst pressure strength and thermal denaturation degree. The parameters were optimized using a genetic algorithm, and the predicted optimum was validated experimentally. Results show significant linear effects of laser power and defocusing amount on burst pressure, with notable interactions between defocusing amount\u2010ICG and ICG\u2010CNT. Laser power and CNT concentration also exhibit significant linear effects on thermal denaturation. The optimal process parameters were a laser power of 6.90\u2009W, defocusing amount \u22120.10\u2009mm, ICG 0.03\u2009wt%, CNT 0.01\u2009wt%.<\/jats:p>","DOI":"10.1002\/jbio.70359","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T05:41:54Z","timestamp":1789364514000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laser Tissue Welding of Esophageal Tissue Assisted by Chitosan\u2010Based Precoating: Process Optimization and Thermal\u2010Mechanical Performance"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5058-7004","authenticated-orcid":false,"given":"Jun","family":"Huang","sequence":"first","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xijing","family":"Yan","sequence":"additional","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mintao","family":"Yan","sequence":"additional","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jincheng","family":"Li","sequence":"additional","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kehong","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Material Science and Technology Nanjing University of Science and Technology  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-010-0805-x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.08.002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-025-00630-6"},{"issue":"29","key":"e_1_2_10_6_1","first-page":"3659","article-title":"Surgical Treatment of Thoracic Esophageal Perforation at Early Phase","volume":"21","author":"Shen Z.","year":"2011","journal-title":"China Journal of Modern Medicine"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1006710"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)34962-1"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.optlastec.2024.111204"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/info15120755"},{"issue":"3","key":"e_1_2_10_11_1","first-page":"176","article-title":"A Review on the Research Progress of Genetic Algorithm","volume":"36","author":"Wu M.","year":"2008","journal-title":"Machine Tools and Hydraulics"},{"issue":"8","key":"e_1_2_10_12_1","first-page":"204","article-title":"Optimization of Injection Molding Process Parameters of Air Purifier Shell Based on Orthogonal Test and BP Neural Network\u2010Genetic Algorithm","volume":"15","author":"Gao H. 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