{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:56:20Z","timestamp":1790556980444,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study evaluated the combined effects of microwave\u2010assisted\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Opuntia humifusa<\/jats:italic>\n                    <\/jats:styled-content>\n                    extract (MA\u2010OHE) and Red\u2010LED irradiation on intracellular redox status and Wnt\/\u03b2\u2010catenin\u2010associated signaling in human hair follicle dermal papilla cells (HFDPCs). Cell viability, DCF fluorescence, DNA damage, and Wnt3a\/\u03b2\u2010catenin expression were assessed. All treatments maintained &gt;\u200990% cell viability and did not significantly increase DNA damage. MA\u2010OHE and Red\u2010LED irradiation reduced DCF fluorescence by approximately 20%\u201325%, with the combined treatment showing the greatest reduction. Western blotting showed increased Wnt3a and total \u03b2\u2010catenin expression, with the combined treatment producing the greatest numerical responses. These findings indicate that MA\u2010OHE pretreatment followed by Red\u2010LED irradiation may provide greater modulation of intracellular redox status and Wnt\/\u03b2\u2010catenin\u2010associated protein expression than either treatment alone. However, true synergy and direct hair growth promotion were not established.\n                  <\/jats:p>","DOI":"10.1002\/jbio.70360","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:12:48Z","timestamp":1789186368000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combined Effects of Microwave\u2010Assisted\n                    <i>Opuntia humifusa<\/i>\n                    Extract and Red\u2010\n                    <scp>LED<\/scp>\n                    Irradiation on Redox Regulation and Wnt\/\u03b2\u2010Catenin Signaling in\n                    <scp>HFDPCs<\/scp>"],"prefix":"10.1002","volume":"19","author":[{"given":"Le Thi Nhu","family":"Ngoc","sequence":"first","affiliation":[{"name":"Department of Bio\u2010Nano Convergence Gachon University  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju\u2010Young","family":"Moon","sequence":"additional","affiliation":[{"name":"Major in Beauty Convergence Kwangwoon University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4702-0282","authenticated-orcid":false,"given":"Young\u2010Chul","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of BioNano Technology Gachon University  Seongnam\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12010174"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2011.05.002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.20402\/ajbc.2016.0080"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3746\/jkfn.2009.38.12.1679"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-97363-8"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9040271"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2017.1286357"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24193618"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cofs.2017.11.012"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9NJ03144H"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42823-023-00480-9"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-022-5315-1"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-018-2455-3"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2021.33.6.553"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22277"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2024.113080"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202300087"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0023-6438(95)80008-5"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780199637973.001.0001"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2014.10.032"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1211\/jpp.58.1.0014"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-78444-7_17"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1089\/photob.2021.0119"},{"key":"e_1_2_11_25_1","first-page":"614001","article-title":"Mechanisms of Low Level Light Therapy","volume":"6140","author":"Hamblin M. R.","year":"2006","journal-title":"Proceedings of SPIE\u2014The International Society for Optical Engineering"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2021.09.008"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2018.7520"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1698895"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.2101.01032"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22091505"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2026.113529"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2021.04.015"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5101"}],"container-title":["Journal of Biophotonics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.70360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbio.70360","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbio.70360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:21:14Z","timestamp":1790554874000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbio.70360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":32,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jbio.70360"],"URL":"https:\/\/doi.org\/10.1002\/jbio.70360","archive":["Portico"],"relation":{},"ISSN":["1864-063X","1864-0648"],"issn-type":[{"value":"1864-063X","type":"print"},{"value":"1864-0648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70360"}}