{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:40:43Z","timestamp":1793173243570,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005275","name":"Region Hovedstaden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biophotonics"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Artificial Intelligence (AI)\u2010assisted line\u2010field confocal optical coherence tomography (LC\u2010OCT) may support the clinical diagnosis of basal cell carcinoma (BCC). The current model produces frame\u2010level BCC scores (0%\u2013100%), but interpretation is challenging due to false positive frames. We present two novel scan\u2010level metrics: the composite score (percentage of frames scoring 100% per scan) and the stability score (longest sequence of consecutive 100%\u2010score\u2010frames per scan). LC\u2010OCT videos (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009568) from 82 lesions from 52 patients were analyzed, including 18 BCCs and 64 non\u2010BCCs. Both scores were significantly higher for BCCs than for non\u2010BCCs (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001). An exploratory threshold of 48 consecutive frames with 100% AI scores yielded 100% sensitivity (95% CI: 81.5%\u2013100%) and 100% specificity (95% CI: 94.4%\u2013100%). In conclusion, scan\u2010level composite and stability scores demonstrate consistent separation between BCC and non\u2010BCC lesions; however, external validation in independent cohorts is required before clinical implementation.\n                  <\/jats:p>","DOI":"10.1002\/jbio.70374","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:20:33Z","timestamp":1791933633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>AI<\/scp>\n                    \u2010Assisted Basal Cell Carcinoma Analysis in Line\u2010Field Confocal\n                    <scp>OCT<\/scp>\n                    : Exploring Diagnostic Metrics"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6128-0826","authenticated-orcid":false,"given":"Otto","family":"Dideriksen","sequence":"first","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8577-6638","authenticated-orcid":false,"given":"Kevin","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavrielle R.","family":"Untracht","sequence":"additional","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen Denmark"},{"name":"Department of Health Technology Technical University of Denmark  Kongens Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Alshede","family":"Philipsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1250-2035","authenticated-orcid":false,"given":"Merete","family":"Haedersdal","sequence":"additional","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9708-6717","authenticated-orcid":false,"given":"Vinzent Kevin","family":"Ortner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Copenhagen University Hospital\u2014Bispebjerg and Frederiksberg  Copenhagen 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