{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T02:32:03Z","timestamp":1778985123172,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,6,19]],"date-time":"2002-06-19T00:00:00Z","timestamp":1024444800000},"content-version":"vor","delay-in-days":169,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Mater. Res."],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The procedure percutaneous vertebroplasty consists of injecting polymethylmethacrylate cement into vertebral bodies for the treatment of osteoporotic compression fractures and tumors of the spine. Clinicians practicing vertebroplasty commonly alter the mixture of monomer\u2010to\u2010powder recommended by the manufacturer in an effort to decrease viscosity and increase the working time. The purpose of the current study was to measure the effect of varying the monomer\u2010to\u2010powder ratio on the compressive material properties (compressive modulus, yield stress, and ultimate compressive strength) of the cement Simplex P (Stryker\u2010Howmedica\u2010Osteonics, Rutherford, NJ). Cylindrical specimens were prepared using monomer\u2010to\u2010powder ratios of 0.45 to 1.00 mL\/g and tested in compression. Peak compressive material properties occurred at the mixture ratio recommended by the manufacturer (0.5 mL\/g) but decreased as the ratio of monomer to powder was increased. The material properties of specimens cured for 1 hour were significantly less than those for specimens cured for 24 hours. The monomer\u2010to\u2010powder ratio affects the compressive material properties of cement. The clinical significance of these results with respect to vertebroplasty is yet to be determined. \u00a9 2002 Wiley Periodicals, Inc. J Biomed Mater Res (Appl Biomater) 63: 396\u2013399, 2002<\/jats:p>","DOI":"10.1002\/jbm.10258","type":"journal-article","created":{"date-parts":[[2002,9,11]],"date-time":"2002-09-11T02:05:28Z","timestamp":1031709928000},"page":"396-399","source":"Crossref","is-referenced-by-count":52,"title":["The effect of the monomer\u2010to\u2010powder ratio on the material properties of acrylic bone cement"],"prefix":"10.1002","volume":"63","author":[{"given":"Stephen M.","family":"Belkoff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janis C.","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis E.","family":"Jasper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7,31]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"149","article-title":"Percutaneous vertebroplasty with acrylic cement in the treatment of osteoporotic vertebral crush fracture syndrome","volume":"33","author":"Debussche\u2010Depriester C","year":"1991","journal-title":"Neuroradiology"},{"key":"e_1_2_7_3_2","first-page":"166","article-title":"Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty","volume":"33","author":"Galibert P","year":"1987","journal-title":"Neurochirurgie"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199801)41:1<171::AID-ART21>3.0.CO;2-5"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1080150"},{"key":"e_1_2_7_6_2","first-page":"1897","article-title":"Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects","volume":"18","author":"Jensen ME","year":"1997","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.18.2.9536480"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(99)00129-5"},{"key":"e_1_2_7_9_2","first-page":"47","volume-title":"Annual Book of ASTM Standards","author":"American Society for Testing and Materials","year":"1997"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(98)00192-6"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197557030-00017"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820180411"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199722)38:2<155::AID-JBM10>3.0.CO;2-C"},{"key":"e_1_2_7_14_2","unstructured":"JasperL DeramondH MathisJM BelkoffSM.Evaluation of PMMA cements altered for use in vertebroplasty. Presented at the 10th Interdisciplinary Research Conference on Injectible Biomaterials Amiens France March 14\u201315 2000."},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-2769-1"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820150312"}],"container-title":["Journal of Biomedical Materials Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbm.10258","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbm.10258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T21:30:49Z","timestamp":1696887049000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbm.10258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1002\/jbm.10258"],"URL":"https:\/\/doi.org\/10.1002\/jbm.10258","archive":["Portico"],"relation":{},"ISSN":["0021-9304","1097-4636"],"issn-type":[{"value":"0021-9304","type":"print"},{"value":"1097-4636","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}