{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T15:16:05Z","timestamp":1726154165414},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2004,9,13]],"date-time":"2004-09-13T00:00:00Z","timestamp":1095033600000},"content-version":"vor","delay-in-days":3270,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biomed. Mater. Res."],"published-print":{"date-parts":[[1995,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A comparative evaluation of various biomaterials for their resistance to bacterial colonization and encrustation in infecred urine is an important area in urological biomaterials research. This article describes an <jats:italic>in vitro<\/jats:italic> dynamic perfusion system that allows four reactors containing 24 1\u2010in. catheter samples (6 per reactor) to be simultaneously perfused at a constant flow rate by synthetic urine. A common urease\u2010producing urinary pathogen, <jats:italic>Proteus mirabilis<\/jats:italic>, was maintained at a level of 10<jats:sup>6<\/jats:sup> colony\u2010forming units\/mL for 7 days in the dynamic perfusion reactors. The pH and bacterial population were monitored every 24 h and the percentage of encrustation on latex and hydrogel\u2010coated commercial catheter materials gave reproducible results in three different runs, 15.2 \u00b1 3.65% and 13.8 \u00b1 2.58%, respectively. A major issue of inlet clogging due to ascending bacteria or ammonia has been rectified using a dismountable inlet assembly. An incubator coupled with a cooling system allowed accurate temperature maintenance of 37\u00b0C in all four reactors. Results from scanning electron microscopy of some latex samples are also presented. \u00a9 1995 John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/jbm.820291005","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T19:41:53Z","timestamp":1117222913000},"page":"1185-1191","source":"Crossref","is-referenced-by-count":10,"title":["An improved model for bacterial encrustation studies"],"prefix":"10.1002","volume":"29","author":[{"given":"Shantha","family":"Sarangapani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Cavedon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Gage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00510523"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1991.tb15157.x"},{"key":"e_1_2_1_4_2","first-page":"50","article-title":"Electron microscopic study of an infected Foley catheter","volume":"28","author":"Nickel J. 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