{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:47:48Z","timestamp":1791121668405,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,3,27]],"date-time":"2007-03-27T00:00:00Z","timestamp":1174953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomedical Materials Res"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The bioactivity of 34 invert or conventional glasses in the P\u2010free and P\u2010containing Si\u2010Ca\u2010Na system was evaluated by examining the <jats:italic>in vitro<\/jats:italic> HydroxyCarbonateApatite (HCA) formation time. The silica content in the glasses varies between 39.48 and 55 mol %. The surfaces of glasses after soaking in simulated body fluid at 37\u00b0C were analyzed by Fourier transform infraRed spectroscopy and scanning electron microscopy coupled with energy dispersive spectroscopy. To understand the HCA formation mechanism, the modification of the glass surface structure was studied. The aim was to understand, in the Si\u2010Ca\u2010Na\u2010P system, the function of each constituent on glass reactivity. It was noted that the bioactivity of Si\u2010Ca\u2010Na\u2010P glasses depends on the P ratio. One of the P\u2010free glasses is as bioactive as the Hench's Bioglass\u00ae noted 45S5, because it needs 12 h to develop HCA as for Hench's one. In the quaternary system, some of the P\u2010rich and Na, Si\u2010poor glasses are more bioactive than 45S5 (6\u201310 h to obtain HCA). Two phosphorus effects were observed: the repolymerization of the silicate network and the formation of phosphate\u2010modifier cation complexes. \u00a9 2007 Wiley Periodicals, Inc. J Biomed Mater Res 2007<\/jats:p>","DOI":"10.1002\/jbm.a.31228","type":"journal-article","created":{"date-parts":[[2007,3,27]],"date-time":"2007-03-27T19:50:25Z","timestamp":1175025025000},"page":"156-168","source":"Crossref","is-referenced-by-count":63,"title":["Compositional dependence on the <i>in vitro<\/i> bioactivity of invert or conventional bioglasses in the Si\u2010Ca\u2010Na\u2010P system"],"prefix":"10.1002","volume":"83A","author":[{"given":"I.","family":"Lebecq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"D\u00e9sanglois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Leriche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Follet\u2010Houttemane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,3,27]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1151-2916.1995.tb08677.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1151-2916.1991.tb07132.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1151-2916.1998.tb02540.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3093(90)90199-V"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1557\/S0883769400030992"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0272-8842(95)00126-3"},{"key":"e_1_2_5_8_2","first-page":"7","volume-title":"Handbook of Bioactive Ceramics","author":"Hench LL","year":"1990"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3093(89)90011-2"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0142-9612(94)90044-2"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820240607"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3093(05)80556-3"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3093(90)90301-2"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00701080"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820250307"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3093(01)00822-5"},{"key":"e_1_2_5_17_2","unstructured":"HenchLL La TorreG FilhoOP ZanottoE. 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