{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:19:23Z","timestamp":1791173963748,"version":"4.1.0"},"reference-count":141,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomedical Materials Res"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rupture of the anterior cruciate ligament (ACL) is one of the most common ligamentous injuries of the knee. Limitations of allografts and autografts in ACL reconstruction as well as recent advancements in biology and materials science have spurred interest in developing tissue\u2010engineered ACL replacements that have the potential to mimic the native ACL in terms of both biological and mechanical properties. This article reviews the current literature regarding contemporary tissue engineering strategies. The four basic components of tissue engineering, biomaterial scaffolds, cell sources, growth factors, and mechanical stimuli, as applied to the development of tissue\u2010engineered ACL replacement grafts, will be systematically addressed. In addition, animal models that have been used to test these tissue\u2010engineered ACL replacements will also be reviewed. To date, there is no tissue\u2010engineered ACL construct that has been successfully implanted in humans. We expect that continued progress in designing a viable tissue\u2010engineered ACL replacement will accompany rapidly advancing techniques in materials science and biology. \u00a9 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 1614\u20131624, 2014.<\/jats:p>","DOI":"10.1002\/jbm.a.34820","type":"journal-article","created":{"date-parts":[[2013,6,4]],"date-time":"2013-06-04T15:43:39Z","timestamp":1370360619000},"page":"1614-1624","source":"Crossref","is-referenced-by-count":131,"title":["Current tissue engineering strategies in anterior cruciate ligament reconstruction"],"prefix":"10.1002","volume":"102","author":[{"given":"Natalie L.","family":"Leong","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery David Geffen School of Medicine at UCLA Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank A.","family":"Petrigliano","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery David Geffen School of Medicine at UCLA Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"McAllister","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery David Geffen School of Medicine at UCLA Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198003000-00006"},{"key":"e_1_2_8_3_1","article-title":"AOSSM initiates multi\u2010center ACL revision study","volume":"5","author":"Matava MJ","year":"2005","journal-title":"Sports Med"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/00003086-199103000-00031","article-title":"Knee function after surgical or nonsurgical treatment of acute rupture of the anterior cruciate ligament: A randomized study with a long\u2010term follow\u2010up period","volume":"264","author":"Andersson C","year":"1991","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.2106\/00004623-199309000-00009","article-title":"Arthroscopically assisted reconstruction of the anterior cruciate ligament with use of autogenous patellar\u2010ligament grafts. Results after twenty\u2010four to forty\u2010two months","volume":"75","author":"Buss DD","year":"1993","journal-title":"J Bone Joint Surg Am"},{"key":"e_1_2_8_6_1","first-page":"317","article-title":"Rupture of the patellar tendon after use of its central third","volume":"16","author":"Langan P","year":"1987","journal-title":"Orthop Rev"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199604000-00008"},{"key":"e_1_2_8_8_1","first-page":"235","article-title":"Anterior cruciate ligament: Injuries and treatment","author":"Larson RV","year":"1996","journal-title":"Instuct Course Lect"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659302100203"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199203123261102"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738110386185"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2006.01.017"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00114-9"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659202000107"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/00003086-198506000-00027","article-title":"The GORE\u2010TEX expanded polytetrafluoroethylene prosthetic ligament. An in vitro and in vivo evaluation","volume":"196","author":"Bolton CW","year":"1985","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1302\/0301-620X.75B5.8376448","article-title":"The ABC carbon and polyester prosthetic ligament for ACL\u2010deficient knees. Early results in 31 cases","volume":"75","author":"Mody BS","year":"1993","journal-title":"J Bone Joint Surg Br"},{"key":"e_1_2_8_17_1","first-page":"79","article-title":"Remarks on the complications following ACL reconstruction using synthetic ligaments","volume":"19","author":"Savarese A","year":"1993","journal-title":"Ital J Orthop Traumatol"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bioeng.6.040803.140037"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659101900303"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0076-z"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/BLO.0b013e31802c7915"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197501000-00033"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354658301100602"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354658701500104"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.03.012"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199173030-00008"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100180407"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00426-9"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820291107"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100160404"},{"key":"e_1_2_8_31_1","unstructured":"GouletF.Tendons and Ligaments. In: Lanza R Langer R Vacanti J editors. Principles of Tissue Engineering;2011:911\u20139914."},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.10120"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.30261"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2012.07.020"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.02.037"},{"key":"e_1_2_8_36_1","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1002\/jbm.a.32629","article-title":"The phenotypic responses of human anterior cruciate ligament cells cultured on poly(epsilon\u2010caprolactone) and chitosan","volume":"93","author":"Shao HJ","year":"2010","journal-title":"J Biomed Mater Res A"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.01.062"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-005-0891-y"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.03.013"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1243\/09544119JEIM203"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-003-0515-0"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.1999.5.443"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.11.050"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2012.1368"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-052-2_16"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-0266(02)00142-0"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-012-0665-1"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4636(200107)56:1<40::AID-JBM1066>3.0.CO;2-I"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.30233"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008207.2011.634532"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(02)00156-4"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.1519280"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.03.039"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1247730"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-012-4781-5"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.05.073"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2006.09.025"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1163\/156856208X386282"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.10.043"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.10167"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/bm015533u"},{"key":"e_1_2_8_62_1","first-page":"6857","volume-title":"Mechanical behavior of electrospun polyurethane. Polymer","year":"2003"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/term.1589"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1089\/107632704322791682"},{"key":"e_1_2_8_65_1","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1002\/jbm.a.32472","article-title":"Design and characterization of a biodegradable composite scaffold for ligament tissue engineering","volume":"92","author":"Hayami JW","year":"2010","journal-title":"J Biomed Mater Res A"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31950"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2012.03.005"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100090504"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(199702)64:2<295::AID-JCB12>3.0.CO;2-I"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.5.700"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(96)00240-2"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1089\/1076327041348428"},{"key":"e_1_2_8_73_1","article-title":"Mesenchymal stem cells for systemic therapy: Shotgun approach or magic bullets?","author":"Millard SM","year":"2012","journal-title":"Bioessays"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453670903278241"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05934"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2011.0649"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2012.0375"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10135"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318221db33"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0559-0"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v019a13"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/term.474"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.07.003"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-009-0581-5"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041320117"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e318168db3e"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2010.0246"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100130206"},{"key":"e_1_2_8_89_1","first-page":"874","article-title":"[Culture of fibroblasts of canine anterior cruciate ligaments in a defined medium, effect of epidermal growth factors and platelet derived growth factors]","volume":"47","author":"Desrosiers EA","year":"1993","journal-title":"Ann Chir"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100150104"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008209709160209"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.30486"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20266"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199506000-00008"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050049"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1089\/tec.2007.0286"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2005.11.41"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20981"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diff.2009.11.001"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512465840"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.10.054"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21112"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.3109\/14653241003709652"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465980260041401"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-007-0385-x"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21111"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2007.02.006"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-011-1458-4"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20367"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198769080-00014"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465990270042301"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.3233\/BIR-1982-19302"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0656fje"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2006.0339"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2006.0434"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1089\/107632703768247313"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2007.0147"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1263\/jbb.102.402"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-012-4710-7"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20050"},{"key":"e_1_2_8_121_1","first-page":"337","article-title":"Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner","volume":"40","author":"Berry CC","year":"2003","journal-title":"Biorheology"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1998.274.5.C1424"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(92)90022-Z"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.32073"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2005.01.014.1100230627"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00531"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0512-0"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.01270"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11420-008-9096-1"},{"key":"e_1_2_8_130_1","first-page":"6857","article-title":"Effect of graft tensioning on mechanical restoration in a rat model of anterior cruciate ligament reconstruction using free tendon graft","volume":"26","author":"Fu SC","year":"2012","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00409"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.04.012"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-007-0320-0"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20073"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20752"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.34229"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2011.0231"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509339915"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.05.048"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2010.00640.x"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.3727\/096368910X536482"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-011-1800-x"}],"container-title":["Journal of Biomedical Materials Research Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbm.a.34820","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbm.a.34820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T20:05:36Z","timestamp":1715457936000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbm.a.34820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,14]]},"references-count":141,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1002\/jbm.a.34820"],"URL":"https:\/\/doi.org\/10.1002\/jbm.a.34820","archive":["Portico"],"relation":{},"ISSN":["1549-3296","1552-4965"],"issn-type":[{"value":"1549-3296","type":"print"},{"value":"1552-4965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,14]]}}}