{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T03:11:38Z","timestamp":1773544298140,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T00:00:00Z","timestamp":1436832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81170641"],"award-info":[{"award-number":["81170641"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81200497"],"award-info":[{"award-number":["81200497"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30901489"],"award-info":[{"award-number":["30901489"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21274018"],"award-info":[{"award-number":["21274018"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shanghai Pujiang Plan","award":["14PJD026"],"award-info":[{"award-number":["14PJD026"]}]},{"DOI":"10.13039\/100007219","name":"Shanghai Municipal Natural Science Foundation","doi-asserted-by":"crossref","award":["13ZR1431700"],"award-info":[{"award-number":["13ZR1431700"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"crossref"}]},{"name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University","award":["LK1408"],"award-info":[{"award-number":["LK1408"]}]},{"name":"DHU Distinguished, Professor Program","award":["A201302"],"award-info":[{"award-number":["A201302"]}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomedical Materials Res"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The goal of this study was to investigate the tissue performance of bladder following stretched electrospun silk fibroin matrix (SESFM) implantation compared with bladder acellular matrix (BAM). We compared SESFM with BAM based on porosity and pore size. Scaffolds were separately transplanted into opposite walls of the bladder of 30 rabbits after stripping the bladder mucosa and smooth muscle (1.5 \u00d7 2.0 cm<jats:sup>2<\/jats:sup>). Gross anatomical observation, histological analysis and muscle contractility studies were performed at 2, 4, and 8 weeks post\u2010op. SESFM has higher porosity and larger pore size compared with BAM (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). At 2 weeks, the presence of vesical calculus was evident in 7\/10 rabbits. Histological analysis showed that SESFM and BAM promoted similar degree of urothelium regeneration (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). However, SESFM promoted a higher degree of smooth muscle and vessel regeneration compared to BAM (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In addition, muscle strips supported by SESFM displayed higher contractile responses to carbachol, KCl, and phenylephrine compared with BAM. At 8 weeks, both matrices elicited similar mild acute and chronic inflammatory reactions. Our results demonstrated that SESFM has greater ability to promote bladder tissue regeneration with structural and functional properties compared to BAM, and with similar biocompatibility. \u00a9 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 9\u201316, 2016.<\/jats:p>","DOI":"10.1002\/jbm.a.35535","type":"journal-article","created":{"date-parts":[[2015,7,7]],"date-time":"2015-07-07T09:09:01Z","timestamp":1436260141000},"page":"9-16","source":"Crossref","is-referenced-by-count":31,"title":["Tissue performance of bladder following stretched electrospun silk fibroin matrix and bladder acellular matrix implantation in a rabbit model"],"prefix":"10.1002","volume":"104","author":[{"given":"Jian\u2010Wen","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue\u2010Min","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao\u2010Bo","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and Engineering, Donghua University Shanghai 201620 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean V.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Medical Center Blvd Winston Salem North Carolina 27157"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weixin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Medical Center Blvd Winston Salem North Carolina 27157"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang\u2010Qiang","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and Engineering, Donghua University Shanghai 201620 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Dong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao\u2010Peng","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and Engineering, Donghua University Shanghai 201620 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u2010Jie","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,14]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"337","article-title":"Histopathological changes of free buccal mucosa and colonic mucosa grafts after translation to dog bladder","volume":"118","author":"Xu YM","year":"2005","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-009-0378-0"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08738.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.06.041"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001920070043"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.01.038"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-007-0066-9"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2012.03230.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091592"},{"key":"e_1_2_5_11_1","first-page":"774","article-title":"Epithelial\u2010differentiated adipose\u2010derived stem cells seeded bladder acellular matrix grafts for urethral reconstruction: an animal model","volume":"20","author":"Li H","year":"2014","journal-title":"Tissue Eng Part A"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.06.013"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2013.0103"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-010-0508-8"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2009.02.014"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(01)00350-7"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820280310"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.07.044"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2011.379"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.05.002"},{"key":"e_1_2_5_21_1","doi-asserted-by":"crossref","unstructured":"TuDD ChungYG GilES SethA FranckD CristofaroV SullivanMP DiVizioD GomezPIII AdamRM KaplanDL EstradaCRJr MauneyJR.Bladder tissue regeneration using acellular bi\u2010layer silk scaffolds in a large animal model of augmentation cystoplasty.Biomaterials2013;34:8681\u20138689.","DOI":"10.1016\/j.biomaterials.2013.08.001"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.09.051"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.03.038"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.06.067"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2013.01.033"},{"key":"e_1_2_5_26_1","doi-asserted-by":"crossref","unstructured":"HuangJW XieMK ZhangY WeiGJ LiX LiHB WangJH ZhuWD LiC XuYM SongLJ.Reconstruction of penile urethra with the 3\u2010dimensional porous bladder acellular matrix in a rabbit model.Urology2014;84:1499\u20131505.","DOI":"10.1016\/j.urology.2014.07.044"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.04.016"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.02.047"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2011.0235"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.05.065"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.03.030"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.01.005"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(03)00519-2"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2011.0390"}],"container-title":["Journal of Biomedical Materials Research Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbm.a.35535","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbm.a.35535","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:00:40Z","timestamp":1696330840000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbm.a.35535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,14]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1002\/jbm.a.35535"],"URL":"https:\/\/doi.org\/10.1002\/jbm.a.35535","archive":["Portico"],"relation":{},"ISSN":["1549-3296","1552-4965"],"issn-type":[{"value":"1549-3296","type":"print"},{"value":"1552-4965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,14]]}}}