{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T06:26:14Z","timestamp":1776839174778,"version":"3.51.2"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T00:00:00Z","timestamp":1555027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomedical Materials Res"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To evaluate the properties and efficacy of a novel braided biodegradable stent (BBS) consisting of poly (p\u2010dioxanone) (PPDO) and polycaprolactone (PCL) for usage in children with congenital cardiovascular diseases. PCL\/PPDO composite filaments were fabricated by coating PCL layers onto PPDO filaments, which were fused with PPDO monofilaments to form the BBS. Physical properties of BBSs including elastic recovery rate, deformation rate, and mechanical characteristics with adjunctive post\u2010dilation were evaluated by radial force\u2010tests. Ten BBS stents and 10 metallic wall stents (WS) as controls were implanted into the common carotid arteries of 10 pigs and angiography as well as histological examinations were performed 4 and 8 weeks after implantation. An 8 mm BBS with adjunctive post\u2010dilation had the best morphological retention and dimension stability being similar to an 8 mm WS. Luminal gain percentages of BBS and WS immediately, 4 weeks and 8 weeks after implantation were 20.44\u2009\u00b1\u20092.82% and 27.08\u2009\u00b1\u20090.88%, 12.34\u2009\u00b1 0.18% and 17.32\u2009\u00b1\u20098.24%, as well as \u22121.76\u2009\u00b1\u20092.45% and\u2009\u2212\u20090.98\u2009\u00b1 3.23%. Luminal areas, internal elastic laminas, neointimal areas, neointimal thicknesses, and area stenosis were not significantly different at 4 weeks and 8 weeks after implantation. Injury and inflammation were similar in both groups and no malposition, thrombosis or dissection occurred. BBS with adjunctive post\u2010dilation showed good physical properties and mechanical stability noninferior to WS. <jats:italic>In vivo<\/jats:italic> evaluations showed that a BBS with post\u2010ballooning had similar short\u2010term outcomes as a WS. \u00a9 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 1667\u20131677, 2019.<\/jats:p>","DOI":"10.1002\/jbm.a.36682","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T01:46:33Z","timestamp":1553737593000},"page":"1667-1677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["A novel braided biodegradable stent for use in congenital heart disease: Short\u2010term results in porcine iliac artery"],"prefix":"10.1002","volume":"107","author":[{"given":"Jing","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University  Shanghai 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