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A total of 39 six\u2010month\u2010old New Zealand White rabbits were randomly divided into four groups of nine rabbits, and bilateral crush or cut off injuries were made on each animal's face. Three rabbits were classified as the healthy control. The facial nerves were cut or crushed and then were either untreated or wrapped with a collagen conduit plus bFGF. At the 15, 30, and 90\u2009days after the injury, three rabbits in each group were sacrificed. Regeneration of the injured facial nerve was evaluated using electrophysiological examination (compound muscle action potentials, CAMPs), scanning electron microscopy, and histological observation. The results suggested that using collagen conduits with recombinant proteins CBD\u2010bFGF to repair facial nerves with crush or cut off injuries promoted functional facial nerve recovery. This treatment, as a possible therapeutic for patients with facial nerve injury, requires further investigation.<\/jats:p>","DOI":"10.1002\/jbm.a.36905","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T04:16:57Z","timestamp":1582517817000},"page":"1329-1337","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Repair of facial nerve crush injury in rabbits using collagen plus basic fibroblast growth factor"],"prefix":"10.1002","volume":"108","author":[{"given":"Piao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Plastic &amp; Trauma Surgery, Beijing Stomatological Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Zhao","sequence":"additional","affiliation":[{"name":"Stomatological Hospital Southern Medical University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Beijing Stomatological Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of General Dentistry Beijing Chongwen Hospital of Stomatology Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinling","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Multidisciplinary Treatment Center, Beijing Stomatological Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renji","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Plastic &amp; 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