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Bioresorbable magnesium (Mg) alloy\u2010based implants offer promising alternatives to traditional metallic implants for the treatment of bone fractures because they eliminate the need for implant removal after healing. The Mg\u2010Y\u2010rare\u2010earth (RE)\u2010Zr alloy WE43, designed for orthopedic implants, has received European Conformity mark approval. However, currently, WE43 is not clinically used in certain countries possibly because of concerns related to RE metals. In this study, we investigated the use of a RE\u2010free alloy, namely, Mg\u2010Zn\u2010Zr alloy (ZK30), as an implant for bone fractures. Hydrofluoric acid (HF) treatment was performed to improve the corrosion resistance of ZK30. HF\u2010treated ZK30 (HF\u2010ZK30) exhibited lower corrosion rate and higher biocompatibility than those of WE43 in in vitro experiments. After implanting a rod of HF\u2010ZK30 into the fractured femoral bones of mice, HF\u2010ZK30 held the bones and healed the fracture without deformation. Treatment results of HF\u2010ZK30 were comparable to those of WE43, indicating the potential of HF\u2010ZK30 as a bioresorbable and safe implant for bone repair.<\/jats:p>","DOI":"10.1002\/jbm.a.37673","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:45:13Z","timestamp":1705585513000},"page":"963-972","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fluoride\u2010treated rare earth\u2010free magnesium alloy <scp>ZK30<\/scp>: An inert and bioresorbable material for bone fracture treatment devices"],"prefix":"10.1002","volume":"112","author":[{"given":"Hirotaka","family":"Watanabe","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[{"name":"Faculty of Advanced Science and Technology 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