{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T16:45:16Z","timestamp":1763829916525},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,7,1]],"date-time":"2003-07-01T00:00:00Z","timestamp":1057017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2003,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the study, characterization of the anodized titanium surface was performed. In addition, histological evaluation and interfacial strength at the bone\u2013implant interface of the characterized surfaces were then evaluated with the use of a rabbit model at 6 and 12 weeks after implantation. Surface treatments consisted of either anodization or anodization followed by hydrothermal treatments. Nontreated titanium surfaces were used as controls in this study. Using scanning\u2010electron microscopy, porous oxide layers were observed on surfaces of anodized titanium implants, whereas porous oxide layers and HA needles were observed on anodized titanium implants following hydrothermal treatments. X\u2010ray diffraction analysis showed the oxide layers were consisted mainly of anatase and a little of rutile. By the hydrothermal treatment on the anodizing surface, HA peaks, as well as the peaks of anatase and trace amounts of rutile peaks were observed. In EPMA analysis, the Ca\/P ratio for the anodic oxide was 1.54 for anodized surfaces, whereas the Ca\/P ratios for HA needles and the anodic oxide were 1.64 and 0.57, respectively, for anodized surfaces following hydrothermal treatments. Although no significant difference was observed for the percent bone contact on all implants evaluated in the <jats:italic>in vivo<\/jats:italic> study, the removal torque strength was significantly higher for anodized implants (48.02 \u00b1 5.92 N\/cm) than the untreated implants (controls) (27.83 \u00b1 1.78 N\/cm) at 6 weeks after implantation. As such, it was concluded that the surface anodized implants resulted in a high interfacial strength at an early implantation period as compared to the nontreated titanium implants. \u00a9 2003 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 66B: 520\u2013525, 2003<\/jats:p>","DOI":"10.1002\/jbm.b.10042","type":"journal-article","created":{"date-parts":[[2003,7,10]],"date-time":"2003-07-10T10:06:44Z","timestamp":1057831604000},"page":"520-525","source":"Crossref","is-referenced-by-count":77,"title":["<i>In vivo<\/i> histological response to anodized and anodized\/hydrothermally treated titanium implants"],"prefix":"10.1002","volume":"66B","author":[{"given":"Won\u2010woo","family":"Son","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010in","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joo L.","family":"Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyo\u2010han","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(83)90359-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1557\/PROC-55-351","article-title":"Chemical composition and morphology of titanium surface oxides","volume":"55","author":"Lausma J","year":"1986","journal-title":"Mater Res Soc Symp Proc"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4686(95)00465-3"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00120418"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820281206"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820250708"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008840026907"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00701236"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820290110"},{"key":"e_1_2_6_11_2","first-page":"331","article-title":"Surface analysis of anodic oxide films containing P on titanium","volume":"17","author":"Zhu X","year":"2001","journal-title":"Int J Oral Maxillofac Implants."},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00394-X"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.10105"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(02)00325-3"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/02844319709051531"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(97)00018-5"},{"key":"e_1_2_6_17_2","first-page":"69","article-title":"Integration of screw implants in the rabbit: A 1\u2010year follow\u2010up of removal torque of titanium implants","volume":"2","author":"Johansson C","year":"1987","journal-title":"Int J Oral Maxillofacial Implants"},{"key":"e_1_2_6_18_2","first-page":"506","article-title":"Does titanium surface treatment influence the bone\u2013implant interface? 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