{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T10:34:30Z","timestamp":1776940470972,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,9,13]],"date-time":"2005-09-13T00:00:00Z","timestamp":1126569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Electron beam irradiation at doses below 150 kGy is a widely used technique to obtain highly crosslinked ultra\u2010high\u2010molecular\u2010weight polyethylene (UHMWPE). Its current use in total joint replacement components may improve wear resistance and decrease UHMWPE particle debris. However, currently used post\u2010irradiation thermal treatments, which aim to decrease the free radicals within the material, introduce microstructural changes that affect UHMWPE mechanical properties, particularly the fatigue strength. This influence may be crucial in total knee replacements, where fatigue\u2010related damage limits the lifespan of the prosthesis. Therefore, more studies are required to understand UHMWPE fatigue after current crosslinking protocols. This study was planned to evaluate the influence of UHMWPE remelting after irradiation on the material fatigue resistance. The remelting was achieved at 150\u00b0C for 2 h on UHMWPE previously irradiated at 50, 100, and 150 kGy. Fatigue evaluation included short\u2010term tests under cyclic tensile stress with zero load ratio, R = 0, and 1 Hz. In addition, stress\u2010life testing was performed using 12% yield as the criterion for failure. Near\u2010threshold fatigue crack propagation experiments were also performed at a frequency of 5 Hz, and crack length was measured in nonthermally treated and remelted irradiated UHMWPE. Crystallinity percentage was calculated from DSC measurements. The results pointed out that irradiation positively contributed to total life analysis, but the further remelting process decreased the flaw initiation resistance. On the other hand, both processes negatively affected the fatigue resistance of notched components. From a clinical point of view, the results suggest that the material fatigue behavior should be carefully studied in new UHMWPE to avoid changes related to material processing. \u00a9 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006<\/jats:p>","DOI":"10.1002\/jbm.b.30378","type":"journal-article","created":{"date-parts":[[2005,9,13]],"date-time":"2005-09-13T21:17:38Z","timestamp":1126646258000},"page":"346-353","source":"Crossref","is-referenced-by-count":54,"title":["Influence of the remelting process on the fatigue behavior of electron beam irradiated UHMWPE"],"prefix":"10.1002","volume":"76B","author":[{"given":"J. A.","family":"Pu\u00e9rtolas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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