{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:45:41Z","timestamp":1758905141798},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,10,15]],"date-time":"2007-10-15T00:00:00Z","timestamp":1192406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Concerns remain regarding the oxidative resistance of highly crosslinked polyethylene (PE). The study investigated the <jats:italic>in vivo<\/jats:italic> performance of Durasul highly crosslinked PE by comparing the oxidation index, density, and percent crystallinity in the weightbearing and nonweightbearing region of retrieved components with unused time zero tibial components. Retrieved and unused Sulene conventional PE tibial components were examined for comparison and the effects of shelf age, <jats:italic>in vivo<\/jats:italic> duration, and <jats:italic>ex vivo<\/jats:italic> duration were also investigated. The oxidation index was not significantly different between unused time zero and retrieved Durasul PE components. Regression analysis data supported these findings in that neither shelf age, <jats:italic>in vivo<\/jats:italic> duration, nor <jats:italic>ex vivo<\/jats:italic> duration was a significant predictor of oxidation index in the retrieved Durasul PE components. In contrast, the retrieved conventional PE components had significantly greater oxidation index, density, and percent crystallinity compared with unused time zero PE components. Regression data suggested that <jats:italic>in vivo<\/jats:italic> and <jats:italic>ex vivo<\/jats:italic> duration, but not shelf aging, influenced the changes observed in the conventional PE components. These data also showed that <jats:italic>in vivo<\/jats:italic> loading did not significantly affect the oxidation index, density, or percent crystallinity in either the retrieved Durasul or conventional PE tibial components. This investigation demonstrates that changes in oxidation index, density, and percent crystallinity of retrieved Durasul PE components after short\u2010term <jats:italic>in vivo<\/jats:italic> durations are likely not a clinical concern. These data should be used as a benchmark to compare with future studies examining the long\u2010term oxidative resistance of Durasul highly crosslinked PE tibial components. \u00a9 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008<\/jats:p>","DOI":"10.1002\/jbm.b.30957","type":"journal-article","created":{"date-parts":[[2007,10,15]],"date-time":"2007-10-15T19:47:34Z","timestamp":1192477654000},"page":"385-397","source":"Crossref","is-referenced-by-count":7,"title":["Examining the influence of short\u2010term implantation on oxidative degradation in retrieved highly crosslinked polyethylene tibial components"],"prefix":"10.1002","volume":"85B","author":[{"given":"B. M.","family":"Willie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. J.","family":"Foot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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