{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:20:06Z","timestamp":1792653606572,"version":"4.5.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,1,20]],"date-time":"2010-01-20T00:00:00Z","timestamp":1263945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Contemporary medical science is reliant upon the rational selection and utilization of devices, and therefore, an increasing need has developed for <jats:italic>in vitro<\/jats:italic> systems aimed at replicating the conditions to which urological devices will be subjected to during their use <jats:italic>in vivo.<\/jats:italic> We report the development and validation of a novel continuous flow encrustation model based on the commercially available CDC biofilm reactor. <jats:italic>Proteus mirabilis<\/jats:italic>\u2010induced encrustation formation on test biomaterial sections under varying experimental parameters was analyzed by X\u2010ray diffraction, infrared\u2010 and Raman spectroscopy and by scanning electron microscopy. The model system produced encrusted deposits similar to those observed in archived clinical samples. Results obtained for the system are highly reproducible with encrustation being rapidly deposited on test biomaterial sections. This model will have utility in the rapid screening of encrustation behavior of biomaterials for use in urological applications. \u00a9 2010 Wiley Periodicals, Inc. 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