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The aim of this study is to evaluate the biomechanical and bone\u2010bonding ability of partly laser\u2010modified implants compared with machined implants after a healing period of 6 months in a rabbit model. The results showed a 170% increase in removal torque. Histology and scanning electron microscopy demonstrated osseointegration for both implant types, but also revealed a different fracture pattern at the interface and in the bone. Transmission electron microscopy and chemical analysis showed coalescence between mineralized tissue and the nano\u2010structured surface of the laser modified implant. Taken together, the results indicate that nano\u2010structured surfaces promote <jats:italic>in vivo<\/jats:italic> long\u2010term bone bonding and interface strength. \u00a9 2011 Wiley Periodicals, Inc. 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