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However, implantation injuries and long\u2010term presence of foreign material often promotes significant luminal tissue growth, leading to a narrowing of the artery and severely restricted blood flow. A promising method to mitigate this process is the use of biodegradable metallic stents, but thus far they have either degraded too slowly (iron) or disappeared prematurely (magnesium). The present work investigates the use of a unique type of magnetic material, galfenol (iron\u2010gallium), for postoperative wireless control of stent degradation rates. Due to its magnetoelastic property, galfenol experiences longitudinal micron\u2010level elongations when exposed to applied magnetic fields, allowing generation of a microstirring effect that affect its degradation behavior. <jats:italic>In vitro<\/jats:italic> indirect cytotoxicity tests on primary rat aortic smooth muscle cells indicated that galfenol byproducts must be concentrated approximately seven times from collected 60 day degradation medium to cause \u223c15% of death from all cells. Surface and cross\u2010sectional characterization of the material indicate that galfenol (Fe<jats:sub>80<\/jats:sub>Ga<jats:sub>20<\/jats:sub>) degradation rates (\u223c0.55% per month) are insufficient for stenting applications. While this material may not be ideal for comprising the entire stent, there is potential for use in combination with other materials. Furthermore, the ability to control degradation rates postimplantation opens new possibilities for biodegradable stents; additional magnetoelastic materials should be investigated for use in stenting applications. \u00a9 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 107B: 232\u2013241, 2019.<\/jats:p>","DOI":"10.1002\/jbm.b.34114","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:54:50Z","timestamp":1521852890000},"page":"232-241","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Magnetoelastic galfenol as a stent material for wirelessly controlled degradation rates"],"prefix":"10.1002","volume":"107","author":[{"given":"Andrew","family":"DeRouin","sequence":"first","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Guillory","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weilue","family":"He","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Frost","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keat Ghee","family":"Ong","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Michigan Technological University Houghton Michigan 49931"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1109\/MEMB.2004.1310967"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","unstructured":"HermawanH MantovaniD.New generation of medical implants: metallic biodegradable coronary stent. 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