{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T17:36:20Z","timestamp":1767980180314,"version":"3.49.0"},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T00:00:00Z","timestamp":1560470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Autogenous bone grafting requires a donor site and may lose substantial volume during remodeling. Several bone replacement materials (BRMs) are under development to overcome these limitations, especially for indications for minimally intervention surgeries. The objective of our study was to assess the potential of an equine collagen cone reinforced with biphasic calcium phosphate (CC\u2010BCP) particles and deproteinized bovine bone matrix (BBM) coated with polylactic acid, and poly\u2010<jats:italic>\u03b5<\/jats:italic>\u2010caprolactone copolymer (BBM\u2010PCC) and then to compare the outcomes with a deproteinized BBM and an equine CC without a filler in a sheep sinus grafting model in the Elleven female sheep were selected. Two experimental sites on each side of the animals were prepared using an extraoral approach for maxillary sinus wall. The four treatments were performed in each animal through a standardized 10\u2010mm access window. While the BBM access was covered with a collagen membrane, all other sites were closed with an equine collagen membrane. All animals were euthanized after 16\u2009weeks. New bone (NB), residual graft particles, and connective tissue were measured in undemineralized resin\u2010embedded sections. As a result, one sheep did not survive the surgery. All sites in the remaining 10 sheep healed uneventfully. All CC and BBM\u2010PCC grafts resorbed and failed to augment the sinuses. BBM and CC\u2010BCP, in contrast, showed some histologic evidence of NB and surgical site augmentation. The NB fraction in the latter two groups accounted for 10 <jats:italic>\u00b1<\/jats:italic> 9 and 4 <jats:italic>\u00b1<\/jats:italic> 5%, respectively (<jats:italic>p<\/jats:italic> &gt;\u20090.05). In conclusion, BBM\u2010PCC and collagen cone performed poorly for sinus floor augmentation, while deproteinised BBM and reinforced collagen cone demonstrated comparable outcomes<\/jats:p>","DOI":"10.1002\/jbm.b.34429","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T12:17:07Z","timestamp":1560514627000},"page":"750-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Biphasic calcium phosphate and polymer\u2010coated bovine bone matrix for sinus grafting in an animal model"],"prefix":"10.1002","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8031-5827","authenticated-orcid":false,"given":"Yevgeny","family":"Sheftel","sequence":"first","affiliation":[{"name":"Division of Periodontology, Department of Oral Sciences University of Otago  Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Ruddiman","sequence":"additional","affiliation":[{"name":"Division of Periodontology, Department of Oral Sciences University of Otago  Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Schmidlin","sequence":"additional","affiliation":[{"name":"Division of Periodontology and Peri\u2010implant Diseases, Clinic of Preventive Dentistry, Periodontology and Cariology Center of Dental Medicine, University of Zurich  Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warwick","family":"Duncan","sequence":"additional","affiliation":[{"name":"Division of Periodontology, Department of Oral Sciences University of Otago  Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.139.2.5751"},{"issue":"1","key":"e_1_2_6_3_1","first-page":"83","article-title":"New bone formation following sinus membrane elevation without bone grafting: Histologic findings in humans","volume":"26","author":"Ahn J.\u2010J.","year":"2011","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12652"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02385.x"},{"issue":"2","key":"e_1_2_6_6_1","article-title":"The influence of Bio\u2010Oss Collagen on healing of an extraction socket: An experimental study in the dog","volume":"28","author":"Ara\u00fajo M.","year":"2008","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01920.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.04.010"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.6.4.284"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12702"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.10.036"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.1288"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1982.tb00172.x"},{"key":"e_1_2_6_15_1","unstructured":"DuncanW. 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