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In computational designs, however, the time and stretch direction dependences of the TMJ soft tissues behavior are not considered and they are frequently based on measurements taken from non\u2010human species or from joints that differ markedly from the human TMJ. The aim of this study was to accurately characterize the porous\u2010fibrous properties of the TMJ soft tissues by simulating previously published experimental tests, to assist professionals in the design of new TMJ implants. To that end, material parameters were determined assuming a uniform fiber orientation throughout the entire sample. This assumption was then tested by comparing these results with those of considering multiple regions and distinct fiber orientations in each sample. Our findings validated the use of a transversely isotropic hyperelastic material model to characterize the direction dependent behavior of TMJ soft tissues and its combination with porous hyperfoam material models to mimic the compressive response of the TMJ disc. In conclusion, constitutive model proposed accurately reproduce the mechanical response of the TMJ soft tissues at different strain rates and stretch directions.<\/jats:p>","DOI":"10.1002\/jbm.b.34558","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T12:50:26Z","timestamp":1579265426000},"page":"2204-2217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Computational characterization of the porous\u2010fibrous behavior of the soft tissues in the temporomandibular joint"],"prefix":"10.1002","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6186-5695","authenticated-orcid":false,"given":"Javier","family":"Ort\u00fan\u2010Terrazas","sequence":"first","affiliation":[{"name":"Group of Biomaterials, Arag\u00f3n Institute of Engineering Research (I3A) University of Zaragoza  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Cego\u00f1ino","sequence":"additional","affiliation":[{"name":"Group of Biomaterials, Arag\u00f3n Institute of Engineering Research (I3A) University of Zaragoza  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaya","family":"P\u00e9rez del Palomar","sequence":"additional","affiliation":[{"name":"Group of Biomaterials, Arag\u00f3n Institute of Engineering Research (I3A) University of Zaragoza  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2006.12.ft-62"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.morpho.2016.06.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(96)00035-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800030601"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(02)00135-3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.08.019"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijos.2014.4"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/10763270360727991"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-005-1741-y"},{"key":"e_1_2_7_11_1","article-title":"A comparison of the mechanical properties of the goat temporomandibular joint disc to the mandibular condylar cartilage in unconfined compression","volume":"2011","author":"Hagandora C. 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