{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:19:56Z","timestamp":1778545196366,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,3]],"date-time":"2020-05-03T00:00:00Z","timestamp":1588464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102018R1A5A2024418"],"award-info":[{"award-number":["NRF\u20102018R1A5A2024418"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to investigate the effects of the incorporation of elastin\u2010like polypeptide (ELP) on the adhesion maturation of mineral trioxide aggregates (MTA). Two types of ELPs (V125 and V125E8) were genetically synthesized. V125 consisted of 125 repeating pentapeptides (Val\u2010Pro\u2010Gly\u2010Xaa\u2010Gly) and V125E8 was functionalized with octaglutamic acid in the C\u2010terminus of V125; both were diluted to 10 wt% in solution. Three 1.5\u2009mm diameter holes in dentin discs were filled with MTA mixed with either a solution of ELP or deionized water. Push\u2010out bond strength tests were performed following storage in simulated body fluid (SBF) for 1, 2, 4, and 8\u2009weeks (<jats:italic>n<\/jats:italic> = 12). The interface between dentin and MTA was observed via scanning electron microscopy (SEM). The maturation of MTA was evaluated with a stereoscopic microscope and SEM. The incorporation of a specific ELP (V125E8) significantly increased the bond strength of MTA to dentin with regard to every maturation period (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The bond strength of MTA also significantly increased with a longer maturation time irrespective of ELP incorporation (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). V125E8\u2010incorporated MTA exhibited a more intimate interface with dentin compared to the other groups. More spindle\u2010shaped crystal structures and thicker crystals were observed in all MTA mixtures as the storage duration increased even though V125E8 exhibited fewer crystal structures on the surface. Within the limitations of this study, the incorporation of V125E8 increased the adhesive properties of MTA and the maturation of MTA occurred regardless of ELP incorporation.<\/jats:p>","DOI":"10.1002\/jbm.b.34616","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T04:24:23Z","timestamp":1588566263000},"page":"2847-2856","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of elastin\u2010like polypeptide incorporation on the adhesion maturation of mineral trioxide aggregates"],"prefix":"10.1002","volume":"108","author":[{"given":"Hyun\u2010Jung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry Kyung Hee University Dental Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang Sik","family":"Lee","sequence":"additional","affiliation":[{"name":"Environmnetal Disease Research Center Korea Research Institute of Bioscience and Biotechnology  Daejeon South Korea"},{"name":"Department of Nanobiotechnology, KRIBB School of Biotechnology University of Science and Technology  Daejeon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyoung","family":"Jeong","sequence":"additional","affiliation":[{"name":"Environmnetal Disease Research Center Korea Research Institute of Bioscience and Biotechnology  Daejeon South Korea"},{"name":"Department of Nanobiotechnology, KRIBB School of Biotechnology University of Science and Technology  Daejeon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duck Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry Kyung Hee University Dental Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung\u2010Wuk","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Bioengineering University of California in Berkeley  Berkeley California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun\u2010Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Dental Research Institute, School of Dentistry Seoul National University  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.02.026"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200305469"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2241-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.03.004"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2005.08.009"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2006.01135.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.11.002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/bp0503742"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.07.043"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1996.0058"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2006.03.004"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2006.01077.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2005.10.043"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-23577-y"},{"key":"e_1_2_6_16_1","first-page":"1","article-title":"Enhancing effect of Elastinlike polypeptide\u2010based matrix on the physical properties of mineral trioxide aggregate","volume":"44","author":"Jang J. 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