{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T15:32:50Z","timestamp":1767108770369},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Foley urinary catheters were coated by chlorhexidine\u2010loaded micelles and chlorhexidine\u2010loaded nanospheres. In our prior study, the nanocoating of Foley urinary catheter was investigated for chlorhexidine\u2010release study, degradation, antibacterial evaluation, and cytotoxicity assessment. These studies presented the 1 month antibacterial property of nanocoating deposited via the layers of micelles and nanospheres. In this study, we evaluated the biocompatibility of these catheters, including hemocompatibility, skin irritation, skin sensitization, and stability during the age of coated urinary catheter. Results demonstrated that coated urinary catheters presented slight hemolysis, whereas skin irritation on rabbit and skin sensitization on Dunkin Hartley guinea pig showed no signs of dermal toxicity, which indicated that inflammation, redness, and swelling did not occur. Moreover, the stability of coated urinary catheters during storage indicated no change in chlorhexidine peaks by high performance liquid chromatography. Information from these studies supports the biocompatibility of coated urinary catheters via nanocoating and their use as indwelling devices to prevent urinary tract infections.<\/jats:p>","DOI":"10.1002\/jbm.b.34718","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T15:47:47Z","timestamp":1601048867000},"page":"496-504","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Biocompatibility and stability during storage of Foley urinary catheters coated chlorhexidine loaded nanoparticles by nanocoating: in vitro and in vivo evaluation"],"prefix":"10.1002","volume":"109","author":[{"given":"Siriwan","family":"Srisang","sequence":"first","affiliation":[{"name":"Department of Engineering King Mongkut's Institute of Technology Ladkrabung, Prince of Chumphon campus  Chumphon Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atthaporn","family":"Boongird","sequence":"additional","affiliation":[{"name":"Department of Surgery, Neurosurgical Unit, Faculty of Medicine Ramathibodi Hospital, Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malyn","family":"Ungsurungsie","sequence":"additional","affiliation":[{"name":"Research and Development Division S and J International Enterprises Public Company Limited  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pimpaka","family":"Wanasawas","sequence":"additional","affiliation":[{"name":"Research and Development Division S and J International Enterprises Public Company Limited  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norased","family":"Nasongkla","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Faculty of Engineering Mahidol University  Nakhon Pathom Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2019.04.018"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2019.05.051"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.34567"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.34155"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2018.11.019"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10837450.2018.1502317"},{"key":"e_1_2_8_8_1","first-page":"1","article-title":"Multilayer nanocoating of Foley urinary catheter by chlorhexidine\u2010loaded nanoparticles for prolonged release and anti\u2010infection of urinary tract","author":"Srisang S","year":"2019","journal-title":"Int J Polym Mater Polym Biomater"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33709"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2018.07.016"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-015-5418-2"},{"key":"e_1_2_8_12_1","article-title":"Development of dental implant coating with minocycline\u2010loaded niosome for antibacterial application","volume":"56","author":"Wongsuwan N","year":"2020","journal-title":"J Drug Deliv Sci Technol"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2018.05.075"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2018.01.008"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.05.123"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2478\/intox-2013-0017"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.34389"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0885328220908027"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2018.02.009"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2018.02.007"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-017-5899-2"},{"key":"e_1_2_8_22_1","unstructured":"ASTM F756\u201308 \"Standard practice for assessment of hemolytic properties of materials.\". (2008)."},{"issue":"3","key":"e_1_2_8_23_1","first-page":"129","article-title":"Stability testing of pharmaceutical products","volume":"2","author":"Bajaj S","year":"2012","journal-title":"J App Pharm Sci"},{"key":"e_1_2_8_24_1","first-page":"291","article-title":"Stability testing of pharmaceutical products in a global environment","volume":"5","author":"Kopp S","year":"2006","journal-title":"RAJ Pharma"},{"issue":"2","key":"e_1_2_8_25_1","first-page":"363","article-title":"Effective date of requirement for premarket approval for surgical mesh for transvaginal pelvic organ prolapse repair. Final order","volume":"81","author":"Food and Drug Administration, HHS","year":"2016","journal-title":"Fed Regist"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2018.04.095"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b06899"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radphyschem.2015.09.014"},{"key":"e_1_2_8_29_1","first-page":"102","article-title":"Short\u2010term versus long\u2010term catheterization after vaginal prolapse surgery","volume":"15","author":"Shrestha B","year":"2013","journal-title":"Nepal Med Coll J"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.4137\/CMBD.S11517"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1116\/1.5008816"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-016-1310-8"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.06.064"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.porgcoat.2020.105559"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2018.11.030"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2020.01.009"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2018.08.019"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.9b01263"}],"container-title":["Journal of Biomedical Materials Research Part B: Applied Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbm.b.34718","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbm.b.34718","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbm.b.34718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T17:06:05Z","timestamp":1693760765000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbm.b.34718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,11]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1002\/jbm.b.34718"],"URL":"https:\/\/doi.org\/10.1002\/jbm.b.34718","archive":["Portico"],"relation":{},"ISSN":["1552-4973","1552-4981"],"issn-type":[{"value":"1552-4973","type":"print"},{"value":"1552-4981","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,11]]},"assertion":[{"value":"2020-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}