{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T14:12:52Z","timestamp":1768486372984,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T00:00:00Z","timestamp":1600300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Polyether ether ketone (PEEK) has shown great promise for implant and biomedical applications because of its excellent chemical, mechanical, and biocompatible properties. However, PEEK is bioinert, which causes weak cell adhesion and limits its use for biomedical applications such as bone implants. Therefore, the activation of the PEEK's surface for cell attachment is desirable. In this study, oxygen plasma and gelatin were used to modify PEEK's surface and the effects of surface roughness, wettability, and cell adhesion to the surface were studied. Surface roughness was measured using a laser scanning confocal microscope, and wettability was measured using the sessile drop method. There was no significant difference in the roughness of the three samples. The gelatin\u2010coated surface showed higher wettability than the plasma\u2010modified or control samples. The cell attachment and proliferation rate were assessed by scanning electron microscopy and the XTT assay, respectively. The XTT assay results indicated that a greater number of cells grew on the gelatin\u2010coated PEEK surface than on the control or plasma\u2010treated surfaces. These results confirmed that the plasma and gelatin treatments enhanced the biocompatibility of the PEEK samples. The increase in biocompatibility could make PEEK a better material candidate for treating bone related injuries and defects.<\/jats:p>","DOI":"10.1002\/jbm.b.34726","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T03:25:06Z","timestamp":1600399506000},"page":"622-629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Polyether ether ketone surface modification with plasma and gelatin for enhancing cell attachment"],"prefix":"10.1002","volume":"109","author":[{"given":"Maryam","family":"Mehdizadeh Omrani","sequence":"first","affiliation":[{"name":"School of Engineering University of British Columbia Kelowna British Columbia Canada"},{"name":"Department of Biomedical Engineering Amirkabir University Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3185-8440","authenticated-orcid":false,"given":"Hitendra","family":"Kumar","sequence":"additional","affiliation":[{"name":"School of Engineering University of British Columbia Kelowna British Columbia Canada"},{"name":"Department of Mechanical and Manufacturing Engineering, Biomedical Engineering Graduate Program, Schulich School of Engineering University of Calgary Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed G. 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