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The application of a titanium coating could also be beneficial to address concerns regarding the exposure of PP in an in vivo environment. Many studies have shown that PP, although it is widely accepted as a stable polymer, is subject to oxidation and degradation, such degradation affects the mechanical behavior, that is, the stiffness and tensile strength of PP mesh. Despite the wide clinical use of Ti\u2010PP surgical meshes, no study has yet investigated the residual material properties post clinical deployment and subsequent explantation. In this study, two explanted Ti\u2010PP mesh samples each having different incorporation durations from two patients were examined. Material analysis conducted within this study includes the following techniques: attenuated total reflectance\u2010Fourier transform infrared spectroscopy (ATR\u2010FTIR), Raman spectroscopy, low voltage \u2013 scanning electron microscopy (LV\u2010SEM), backscattered electron (BSE) imaging, energy dispersive X\u2010ray spectroscopy (EDS) and secondary election hyperspectral imaging (SEHI). The hypothesis of this study is that the Ti coating successfully shields the PP mesh from oxidative stress in vivo and thus protects it from degradation. The results of this analysis show for the first time evidence of bulk oxidation, surface degradation, and environmental stress cracking on explanted Ti\u2010PP meshes.<\/jats:p>","DOI":"10.1002\/jbm.b.35221","type":"journal-article","created":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T13:07:20Z","timestamp":1673096840000},"page":"1142-1152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Characterization in respect to degradation of titanium\u2010coated polypropylene surgical mesh explanted from humans"],"prefix":"10.1002","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6761-3600","authenticated-orcid":false,"given":"Nicholas T. 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