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However, in recent years, composite structures arise as an attractive alternative due to high strength to weight ratio and other advantages like, for example, radiolucency. According to Food and Drug Administration (FDA), the only unidirectionally reinforced composite allowed to be implanted in human bodies is carbon fiber (CF)\u2010reinforced poly\u2010ether\u2010ether\u2010ketone (PEEK). In this work, the healing process of long bone assembled with CF\/PEEK plates with cross\u2010 and angle\u2010ply lay\u2010up configurations is studied in the framework of finite element method. The healing is simulated by making use of the mechanoregulation model basing on the Prendergast theory. Cells transformation is determined by the octahedral shear strain and interstitial fluid velocity. The process runs iteratively assuming single load cycle each day. The fracture is subjected to axial and transverse forces. In the computations, the Abaqus program is used. It is shown that the angle\u2010ply lamination scheme of CF\/PEEK composite seems to provide better conditions for the transformation of the soft callus into the bone tissue.<\/jats:p>","DOI":"10.1002\/jbm.b.35463","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T13:24:33Z","timestamp":1723123473000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Bone healing under different lay\u2010up configuration of carbon fiber\u2010reinforced <scp>PEEK<\/scp> composite plates"],"prefix":"10.1002","volume":"112","author":[{"given":"Agnieszka","family":"Sabik","sequence":"first","affiliation":[{"name":"Department of Mechanics of Materials and Structures, Faculty of Civil and Environmental Engineering Gda\u0144sk University of Technology  Gda\u0144sk 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