{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:14:26Z","timestamp":1788502466836,"version":"build-2803163510"},"reference-count":66,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biomed Mater Res"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Biodegradable Mg WE43 alloys offer bone\u2010matched stiffness and osteogenic degradation products for mandibular fracture fixation but undergo unpredictable uniform and pitting corrosion that may compromise early stability. Integrating corrosion kinetics into finite element analysis (FEA) could inform implant design and degradation scheduling. To evaluate mechanical stability and degradation of a Mg WE43 mini\u2010plate for mandibular fractures via finite element analysis (FEA), incorporating uniform corrosion and Weibull\u2010distributed pitting corrosion to model stochastic defect formation and growth. A subject\u2010specific mandibular model with a 1\u2009mm angle fracture gap was reconstructed from CT images and combined with detailed SolidWorks designs of a 1\u2009mm\u2010thick WE43 mini\u2010plate and screws. The assembly was discretized with linear tetrahedral elements in ABAQUS\/Explicit. A custom VUMAT subroutine implemented continuum damage mechanics\u2013based uniform corrosion and Weibull\u2010distributed pitting corrosion. Boundary conditions fixed the temporal region and applied 150\u2013600\u2009N anterior loads. Validation against experimental mass loss and stress\u2013strain data assessed model accuracy. Over 24\u2009days, simulated corrosion decreased plate stiffness by &gt;\u200960%, aligning with typical cortical bridging at ~35% residual stiffness. Ultimate tensile strength dropped from 279 to 123\u2009MPa (56% loss) and strain at failure halved. von Mises stress redistribution shifted peak stresses toward corroded fillets, increasing by &gt;\u200940% under 600\u2009N by day 24. Simulated mass\u2010loss trajectories and stress\u2013strain curves closely matched published experimental benchmarks. The CDM\u2010based FEA framework reliably predicts the time\u2010dependent mechanical degradation of WE43 Mg fixation plates, allowing for the synchronization of implant weakening with bone healing. This predictive tool enables researchers and manufacturers to enhance the implant geometry and corrosion profiles for better safety and effectiveness of biodegradable maxillofacial fixation devices.<\/jats:p>","DOI":"10.1002\/jbm.b.70112","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T05:06:26Z","timestamp":1780895186000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Corrosion\u2010Driven Degradation of Mg\n                    <scp>WE43<\/scp>\n                    Plates for Mandibular Fracture Fixation: An In\u2010Silico Study"],"prefix":"10.1002","volume":"114","author":[{"given":"Reza","family":"Izadi","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Engineering Islamic Azad University  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohadese","family":"Rajaeirad","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Faculty of Engineering University of Isfahan  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandipan","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering SRM Institute of Science and Technology  Kattankulathur Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000177687.83247.27"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0275-7"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100039\u20101693038"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","unstructured":"E.Izci M. 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