{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:04:22Z","timestamp":1790373862984,"version":"4.1.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2013,1,31]],"date-time":"2013-01-31T00:00:00Z","timestamp":1359590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,8,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2003<\/jats:title>\n                  <jats:p>A site-dependent association between obesity and fracture has been reported in postmenopausal women. In this study we investigated the relationship between body mass index (BMI) and fracture at different skeletal sites in older men (\u226565 years). We carried out a population-based cohort study using data from the Sistema d\u2018Informaci\u00f3 per al Desenvolupament de l\u2018Investigaci\u00f3 en Atenci\u00f3 Prim\u00e0ria (SIDIAPQ) database. SIDIAPQ contains the primary care and hospital admission computerized medical records of &amp;gt;1300 general practitioners (GPs) in Catalonia (Northeast Spain), with information on a representative 30% of the population (&amp;gt;2\u2009million people). In 2007, 186,171 men \u226565 years were eligible, of whom 139,419 (74.9%) had an available BMI measurement. For this analysis men were categorized as underweight\/normal (BMI\u2009&amp;lt;\u200925\u2009kg\/m2, n\u2009=\u200926,298), overweight (25\u2009\u2264\u2009BMI\u2009&amp;lt;\u200930\u2009kg\/m2, n\u2009=\u200970,851), and obese (BMI \u2265 30\u2009kg\/m2, n\u2009=\u200942,270). Incident fractures in the period 2007 to 2009 were ascertained using International Classification of Diseases, 10th edition (ICD-10) codes. A statistically significant reduction in clinical spine and hip fractures was observed in obese (relative risk [RR], 0.65; 95% confidence interval [CI], 0.53\u20130.80 and RR, 0.63; 95% CI, 0.54\u20130.74, respectively), and overweight men (RR, 0.77; 95% CI, 0.64\u20130.92 and RR, 0.63; 95% CI 0.55\u20130.72, respectively) when compared with underweight\/normal men. Additionally, obese men had significantly fewer wrist\/forearm (RR, 0.77; 95% CI, 0.61\u20130.97) and pelvic (RR, 0.44; 95% CI, 0.28\u20130.70) fractures than underweight\/normal men. Conversely, multiple rib fractures were more frequent in overweight (RR, 3.42; 95% CI, 1.03\u201311.37) and obese (RR, 3.96; 95% CI, 1.16\u201313.52) men. In this population-based cohort of older men, obesity was associated with a reduced risk of clinical spine, hip, pelvis, and wrist\/forearm fracture and increased risk of multiple rib fractures when compared to normal or underweight men. Further work is needed to identify the mechanisms underlying these associations.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/jbmr.1878","type":"journal-article","created":{"date-parts":[[2013,1,31]],"date-time":"2013-01-31T19:06:25Z","timestamp":1359659185000},"page":"1771-1777","source":"Crossref","is-referenced-by-count":109,"title":["The association between fracture site and obesity in men: A population-Based cohort study"],"prefix":"10.1093","volume":"28","author":[{"given":"Melissa O","family":"Premaor","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Health Sciences CenterFederal University of Santa MariaSanta MariaBrazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet E","family":"Compston","sequence":"additional","affiliation":[{"name":"Cambridge University Hospitals National Health Service (NHS) Foundation TrustCambridgeUK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Fina Avil\u00e9s","sequence":"additional","affiliation":[{"name":"Primary Care Department, Institut Catal\u00e0 de la SalutBarcelonaSpain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aina","family":"Pag\u00e8s-Castell\u00e0","sequence":"additional","affiliation":[{"name":"GREMPAL (Grup de Recerca En Malalties Prevalents de l'Aparell Locomotor) Research Group-USR BarcelonaIDIAP Jordi Gol Primary Care Research Institute \u2013 Universitat Aut\u00f2noma de BarcelonaBarcelonaSpain"},{"name":"Primary Care Department, Institut Catal\u00e0 de la SalutBarcelonaSpain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Nogu\u00e9s","sequence":"additional","affiliation":[{"name":"URFOA (Unitat de Recerca de la Fisiopatologia \u00d2ssia i Articular) and RETICEFIMIM (Parc de Salut Mar) \u2013 Instituto de Salud Carlos IIIBarcelonaSpain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"D\u00edez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"URFOA (Unitat de Recerca de la Fisiopatologia \u00d2ssia i Articular) and RETICEFIMIM (Parc de Salut Mar) \u2013 Instituto de Salud Carlos IIIBarcelonaSpain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Prieto-Alhambra","sequence":"additional","affiliation":[{"name":"Medical Research Council (MRC) Lifecourse Epidemiology UnitUniversity of Southampton, Southampton General HospitalSouthamptonUK"},{"name":"Oxford National Institute for Health and Research (NIHR) Musculoskeletal Biomedical Research UnitNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of OxfordOxfordUK"},{"name":"URFOA (Unitat de Recerca de la Fisiopatologia \u00d2ssia i Articular) and RETICEFIMIM (Parc de Salut Mar) \u2013 Instituto de Salud Carlos IIIBarcelonaSpain"},{"name":"GREMPAL (Grup de Recerca En Malalties Prevalents de l'Aparell Locomotor) Research Group-USR BarcelonaIDIAP Jordi Gol Primary Care Research Institute \u2013 Universitat Aut\u00f2noma de BarcelonaBarcelonaSpain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,1,31]]},"reference":[{"issue":"11","key":"2024020318364136900_jbmr1878-bib-0001","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.amjmed.2011.06.013","article-title":"Siris ES; Glow Investigators. 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