{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:59:21Z","timestamp":1791269961101,"version":"4.1.0"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2013,6,15]],"date-time":"2013-06-15T00:00:00Z","timestamp":1371254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2003<\/jats:title>\n                  <jats:p>Multimodal exercise programs incorporating traditional progressive resistance training (PRT), weight-bearing impact training and\/or balance training are recommended to reduce risk factors for falls and fracture. However, muscle power, or the ability to produce force rapidly, has emerged as a more crucial variable to functional decline than muscle strength or mass. The aim of this 12-month community-based randomized controlled trial, termed Osteo-cise: Strong Bones for Life, was to evaluate the effectiveness and feasibility of a multimodal exercise program incorporating high-velocity (HV)-PRT, combined with an osteoporosis education and behavioral change program, on bone mineral density (BMD), body composition, muscle strength and functional muscle performance in older adults. Falls incidence was evaluated as a secondary outcome. A total of 162 older adults (mean\u2009\u00b1\u2009SD; 67\u2009\u00b1\u20096 years) with risk factors for falls and\/or low BMD were randomized to the Osteo-cise program (n\u2009=\u200981) or a control group (n\u2009=\u200981). Exercise consisted of fitness center-based HV-PRT, weight-bearing impact and challenging balance\/mobility activities performed three times weekly. After 12 months, the Osteo-cise program led to modest but significant net gains in femoral neck and lumbar spine BMD (1.0% to 1.1%, p\u2009&amp;lt;\u20090.05), muscle strength (10% to 13%, p\u2009&amp;lt;\u20090.05), functional muscle power (Timed Stair Climb, 5%, p\u2009&amp;lt;\u20090.05) and dynamic balance (Four Square Step Test 6%, p\u2009&amp;lt;\u20090.01; Sit-to-Stand, 16%, p\u2009&amp;lt;\u20090.001) relative to controls. There was no effect on total body lean mass or mobility (timed-up-and-go), and no difference in falls rate (incidence rate ratio [IRR], 1.22; 95% confidence interval [CI], 0.72\u20132.04). In conclusion, this study demonstrates that the Osteo-cise: Strong Bones for Life community-based, multimodal exercise program represents an effective approach to improve multiple musculoskeletal and functional performance measures in older adults with risk factors for falls and\/or low BMD. Although this did not translate into a reduction in the rate of falls, further large-scale trials are needed to evaluate the efficacy of this multimodal approach on reducing falls and fracture. \u00a9 2014 American Society for Bone and Mineral Research.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/jbmr.2014","type":"journal-article","created":{"date-parts":[[2013,6,15]],"date-time":"2013-06-15T11:09:20Z","timestamp":1371294560000},"page":"182-191","source":"Crossref","is-referenced-by-count":143,"title":["Effects of a Targeted Multimodal Exercise Program Incorporating High-Speed Power Training on Falls and Fracture Risk Factors in Older Adults: A Community-Based Randomized Controlled Trial"],"prefix":"10.1093","volume":"29","author":[{"given":"Jenny","family":"Gianoudis","sequence":"first","affiliation":[{"name":"Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition SciencesDeakin UniversityMelbourneAustralia"},{"name":"NorthWest Academic CentreUniversity of Melbourne, Western HealthMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine A","family":"Bailey","sequence":"additional","affiliation":[{"name":"NorthWest Academic CentreUniversity of Melbourne, Western HealthMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R","family":"Ebeling","sequence":"additional","affiliation":[{"name":"NorthWest Academic CentreUniversity of Melbourne, Western HealthMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caryl A","family":"Nowson","sequence":"additional","affiliation":[{"name":"Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition SciencesDeakin UniversityMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerrie M","family":"Sanders","sequence":"additional","affiliation":[{"name":"NorthWest Academic CentreUniversity of Melbourne, Western HealthMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Hill","sequence":"additional","affiliation":[{"name":"School of PhysiotherapyCurtin UniversityPerthAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin M","family":"Daly","sequence":"additional","affiliation":[{"name":"Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition SciencesDeakin UniversityMelbourneAustralia"},{"name":"NorthWest Academic CentreUniversity of Melbourne, Western HealthMelbourneAustralia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,6,15]]},"reference":[{"issue":"7","key":"2024020318590371600_jbmr2014-bib-0001","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s00198-008-0776-y","article-title":"Effects of a multi-component exercise program and calcium-vitamin-D-3-fortified milk on bone mineral density in older men: a 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