{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:31:30Z","timestamp":1792679490277,"version":"4.5.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2013,7,22]],"date-time":"2013-07-22T00:00:00Z","timestamp":1374451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,2,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\u2003<\/jats:title>\n                    <jats:p>Bone strength is predominantly determined by bone density, but bone microarchitecture also plays an important role. We examined whether trabecular bone score (TBS) predicts the risk of vertebral fractures in a Japanese female cohort. Of 1950 randomly selected women aged 15 to 79 years, we analyzed data from 665 women aged 50 years and older, who completed the baseline study and at least one follow-up survey over 10 years, and who had no conditions affecting bone metabolism. Each survey included spinal imaging by dual-energy X-ray absorptiometry (DXA) for vertebral fracture assessment and spine areal bone mineral density (aBMD) measurement. TBS was obtained from spine DXA scans archived in the baseline study. Incident vertebral fracture was determined when vertebral height was reduced by 20% or more and satisfied McCloskey-Kanis criteria or Genant's grade 2 fracture at follow-up. Among eligible women (mean age 64.1\u2009\u00b1\u20098.1 years), 92 suffered incident vertebral fractures (16.7\/103 person-years). These women were older with lower aBMD and TBS values relative to those without fractures. The unadjusted odds ratio of vertebral fractures for one standard deviation decrease in TBS was 1.98 (95% confidence interval [CI] 1.56, 2.51) and remained significant (1.64, 95% CI 1.25, 2.15) after adjusting for aBMD. The area under the receiver operating characteristic curve of TBS and aBMD combined was 0.700 for vertebral fracture prediction and was not significantly greater than that of aBMD alone (0.673). However, reclassification improvement measures indicated that TBS and aBMD combined significantly improved risk prediction accuracy compared with aBMD alone. Further inclusion of age and prevalent vertebral deformity in the model improved vertebral fracture prediction, and TBS remained significant in the model. Thus, lower TBS was associated with higher risk of vertebral fracture over 10 years independently of aBMD and clinical risk factors including prevalent vertebral deformity. TBS could effectively improve fracture risk assessment in clinical settings. \u00a9 2014 American Society for Bone and Mineral Research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jbmr.2048","type":"journal-article","created":{"date-parts":[[2013,7,22]],"date-time":"2013-07-22T02:14:51Z","timestamp":1374459291000},"page":"399-407","source":"Crossref","is-referenced-by-count":156,"title":["Trabecular Bone Score (TBS) Predicts Vertebral Fractures in Japanese Women Over 10 Years Independently of Bone Density and Prevalent Vertebral Deformity: The Japanese Population-Based Osteoporosis (JPOS) Cohort Study"],"prefix":"10.1093","volume":"29","author":[{"given":"Masayuki","family":"Iki","sequence":"first","affiliation":[{"name":"Department of Public HealthKinki University Faculty of MedicineOsaka-SayamaJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Tamaki","sequence":"additional","affiliation":[{"name":"Department of Public HealthKinki University Faculty of MedicineOsaka-SayamaJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiko","family":"Kadowaki","sequence":"additional","affiliation":[{"name":"Department of Public HealthKinki University Faculty of MedicineOsaka-SayamaJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuho","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Human LifeJin-ai UniversityEchizenJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namiraa","family":"Dongmei","sequence":"additional","affiliation":[{"name":"Department of Public HealthKinki University Faculty of MedicineOsaka-SayamaJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Winzenrieth","sequence":"additional","affiliation":[{"name":"Med-ImapsH\u00f4pital Xavier ArnozanPessacFrance"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadanobu","family":"Kagamimori","sequence":"additional","affiliation":[{"name":"University of ToyamaToyamaJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Kagawa","sequence":"additional","affiliation":[{"name":"Kagawa Nutrition UniversitySakadoJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Yoneshima","sequence":"additional","affiliation":[{"name":"Shuwa General HospitalKasukabeJapan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,7,22]]},"reference":[{"issue":"6","key":"2024020318572880000_jbmr2048-bib-0001","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/0002-9343(93)90218-E","article-title":"Consensus development conference: diagnosis, prophylaxis and treatment of osteoporosis","volume":"94","year":"1993","journal-title":"Am J Med."},{"key":"2024020318572880000_jbmr2048-bib-0002","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1007\/s00198-002-1345-4","article-title":"Bone strength and its determinants","volume":"14","author":"Ammann","year":"2003","journal-title":"Osteoporos Int."},{"issue":"7","key":"2024020318572880000_jbmr2048-bib-0003","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1359\/JBMR.050304","article-title":"Predictive value of aBMD for hip and other fractures","volume":"20","author":"Johnell","year":"2005","journal-title":"J Bone Miner Res."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0004","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1148\/radiol.12110462","article-title":"Osteoporosis imaging: state of the art and advanced imaging","volume":"263","author":"Link","year":"2012","journal-title":"Radiology."},{"issue":"6","key":"2024020318572880000_jbmr2048-bib-0005","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ncprheum0798","article-title":"Technology insight: noninvasive assessment of bone strength in osteoporosis","volume":"4","author":"Bouxsein","year":"2008","journal-title":"Nat Clin Pract Rheumatol."},{"key":"2024020318572880000_jbmr2048-bib-0006","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1749-6632.2009.05378.x","article-title":"Looking beyond bone mineral density: imaging assessment of bone quality","volume":"1192","author":"Griffith","year":"2010","journal-title":"Ann NY Acad Sci."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0007","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jocd.2012.05.001","article-title":"Three-dimensional (3D) microarchitecture correlations with 2D projection image gray-level variations assessed by trabecular bone score using high-resolution computed tomographic acquisitions: effects of resolution and noise","volume":"16","author":"Winzenrieth","year":"2013","journal-title":"J Clin Densitomet."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0008","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jocd.2011.05.005","article-title":"Correlations between trabecular bone score, measured using anteroposterior dual-energy X-ray absorptiometry acquisition, and 3-dimensional parameters of bone microarchitecture: an experimental study on human cadaver vertebrae","volume":"14","author":"Hans","year":"2011","journal-title":"J Clin Densitom."},{"key":"2024020318572880000_jbmr2048-bib-0009","first-page":"7","article-title":"The predictive value of trabecular bone score (TBS) on whole lumbar vertebrae mechanics: an ex vivo study","author":"Roux","year":"2013","journal-title":"Osteoporos Int."},{"issue":"2","key":"2024020318572880000_jbmr2048-bib-0010","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jocd.2008.11.006","article-title":"Evaluation of the potential use of trabecular bone score to complement bone mineral density in the diagnosis of osteoporosis: a preliminary spine BMD-matched case-control study","volume":"12","author":"Pothuaud","year":"2009","journal-title":"J Clin Densitom."},{"issue":"2","key":"2024020318572880000_jbmr2048-bib-0011","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s00223-009-9322-y","article-title":"A retrospective case-control study assessing the role of trabecular bone score in postmenopausal Caucasian women with osteopenia: analyzing the odds of vertebral fracture","volume":"86","author":"Winzenrieth","year":"2010","journal-title":"Calcif Tissue Int."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0012","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.bone.2009.06.032","article-title":"A multicentre, retrospective case-control study assessing the role of trabecular bone score (TBS) in menopausal Caucasian women with low areal bone mineral density (BMDa): analysing the odds of vertebral fracture","volume":"46","author":"Rabier","year":"2010","journal-title":"Bone."},{"issue":"5","key":"2024020318572880000_jbmr2048-bib-0013","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1210\/jc.2012-4255","article-title":"Trabecular bone score (TBS)\u2014a novel method to evaluate bone microarchitectural texture in patients with primary hyperparathyroidism","volume":"98","author":"Silva","year":"2013","journal-title":"J Clin Endocrinol Metab."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0014","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bone.2012.11.041","article-title":"Trabecular bone score\u201d (TBS): an indirect measure of bone micro-architecture in postmenopausal patients with primary hyperparathyroidism","volume":"53","author":"Romagnoli","year":"2013","journal-title":"Bone."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0015","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jocd.2012.01.007","article-title":"Identification of rheumatoid arthritis patients with vertebral fractures using bone mineral density and trabecular bone score","volume":"15","author":"Breban","year":"2012","journal-title":"J Clin Densitom."},{"issue":"11","key":"2024020318572880000_jbmr2048-bib-0016","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1002\/jbmr.499","article-title":"Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: the Manitoba study","volume":"26","author":"Hans","year":"2011","journal-title":"J Bone Miner Res."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0017","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00198-012-2188-2","article-title":"Trabecular bone score improves fracture risk prediction in non-osteoporotic women: the OFELY study","volume":"24","author":"Boutroy","year":"2013","journal-title":"Osteoporos Int."},{"key":"2024020318572880000_jbmr2048-bib-0018","first-page":"26","article-title":"Manitoba Bone Density Program. Clinical factors associated with trabecular bone score","author":"Leslie","year":"2013","journal-title":"J Clin Densitom."},{"key":"2024020318572880000_jbmr2048-bib-0019","doi-asserted-by":"crossref","DOI":"10.1016\/S0002-9343(97)90025-5","article-title":"Clinical consequences of vertebral fractures","author":"Ross","year":"1997","journal-title":"Am J Med."},{"issue":"9527","key":"2024020318572880000_jbmr2048-bib-0020","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1016\/S0140-6736(06)68891-0","volume":"367","author":"Sambrook","year":"2006","journal-title":"Osteoporosis. Lancet."},{"issue":"6","key":"2024020318572880000_jbmr2048-bib-0021","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/ije\/24.6.1171","article-title":"Vertebral fracture prevalence in women in Hiroshima compared to Caucasians or Japanese in the US","volume":"24","author":"Ross","year":"1995","journal-title":"Int J Epidemiol."},{"issue":"7","key":"2024020318572880000_jbmr2048-bib-0022","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s001980170073","article-title":"Bone mineral density of the spine, hip and distal forearm in representative samples of the Japanese female population: Japanese Population-Based Osteoporosis (JPOS) Study","volume":"12","author":"Iki","year":"2001","journal-title":"Osteoporos Int."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0023","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1620\/tjem.207.217","article-title":"Development of a food-frequency questionnaire to measure the dietary calcium intake of adult Japanese women","volume":"207","author":"Sato","year":"2005","journal-title":"Tohoku J Exp Med."},{"issue":"6","key":"2024020318572880000_jbmr2048-bib-0024","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.bone.2008.08.106","article-title":"International Society for Clinical Densitometry 2007 Adult and Pediatric Official Positions","volume":"43","author":"Lewiecki","year":"2008","journal-title":"Bone."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0025","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/BF01623275","article-title":"The assessment of vertebral deformity: a method for use in population studies and clinical trials","volume":"3","author":"McCloskey","year":"1993","journal-title":"Osteoporos Int."},{"issue":"9","key":"2024020318572880000_jbmr2048-bib-0026","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","article-title":"Vertebral fracture assessment using a semiquantitative technique","volume":"8","author":"Genant","year":"1993","journal-title":"J Bone Miner Res."},{"issue":"9","key":"2024020318572880000_jbmr2048-bib-0027","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1007\/s00198-009-1113-9","article-title":"Prevalent vertebral deformity independently increases incident vertebral fracture risk in middle-aged and elderly Japanese women: the Japanese Population-based Osteoporosis (JPOS) Cohort Study","volume":"21","author":"Kadowaki","year":"2010","journal-title":"Osteoporos Int."},{"issue":"11","key":"2024020318572880000_jbmr2048-bib-0028","doi-asserted-by":"crossref","first-page":"919","DOI":"10.7326\/0003-4819-114-11-919","article-title":"Pre-existing fractures and bone mass predict vertebral fracture incidence in women","volume":"114","author":"Ross","year":"1991","journal-title":"Ann Intern Med."},{"issue":"2","key":"2024020318572880000_jbmr2048-bib-0029","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s00774-003-0457-z","article-title":"Absolute height reduction and percent height ratio of the vertebral body in incident fracture in Japanese women","volume":"22","author":"Fukunaga","year":"2004","journal-title":"J Bone Miner Metab."},{"issue":"8","key":"2024020318572880000_jbmr2048-bib-0030","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1359\/jbmr.2003.18.8.1547","article-title":"Fracture prediction from bone mineral density in Japanese men and women","volume":"18","author":"Fujiwara","year":"2003","journal-title":"J Bone Miner Res."},{"issue":"23","key":"2024020318572880000_jbmr2048-bib-0031","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1001\/jama.298.23.2761","article-title":"Long-term risk of incident vertebral fractures","volume":"298","author":"Cauley","year":"2007","journal-title":"JAMA."},{"issue":"4","key":"2024020318572880000_jbmr2048-bib-0032","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S8756-3282(03)00248-5","article-title":"Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS)","volume":"33","author":"Lunt","year":"2003","journal-title":"Bone."},{"key":"2024020318572880000_jbmr2048-bib-0033","first-page":"267","volume-title":"Proceedings of the Second International Symposium on Information Theory","author":"Akaike","year":"1973"},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0034","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics."},{"key":"2024020318572880000_jbmr2048-bib-0035","first-page":"56","volume-title":"Akaike information criterion statistics","author":"Sakamoto","year":"1986"},{"issue":"2","key":"2024020318572880000_jbmr2048-bib-0036","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/sim.2929","article-title":"Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond","volume":"27","author":"Pencina","year":"2008","journal-title":"Stat Med."},{"key":"2024020318572880000_jbmr2048-bib-0037","author":"Kennedy","year":"2010"},{"issue":"8","key":"2024020318572880000_jbmr2048-bib-0038","first-page":"1137","article-title":"Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis","volume":"9","author":"Kanis","year":"1994","journal-title":"J Bone Miner Res."},{"issue":"7","key":"2024020318572880000_jbmr2048-bib-0039","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1093\/aje\/kwj063","article-title":"The inconsistency of \u201coptimal\u201d cutpoints obtained using two criteria based on the receiver operating characteristic curve","volume":"163","author":"Perkins","year":"2006","journal-title":"Am J Epidemiol."},{"issue":"9319","key":"2024020318572880000_jbmr2048-bib-0040","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0140-6736(02)08657-9","article-title":"Epidemiology and outcomes of osteoporotic fractures","volume":"359","author":"Cummings","year":"2002","journal-title":"Lancet."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0041","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00198-002-1316-9","article-title":"European Vertebral Osteoporosis Study. Prevalent vertebral deformities predict increased mortality and increased fracture rate in both men and women: a 10-year population-based study of 598 individuals from the Swedish cohort in the European Vertebral Osteoporosis Study","volume":"14","author":"Hasserius","year":"2003","journal-title":"Osteoporos Int."},{"issue":"7","key":"2024020318572880000_jbmr2048-bib-0042","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s001980070075","article-title":"Risk of mortality following clinical fractures","volume":"11","author":"Cauley","year":"2000","journal-title":"Osteoporos Int."},{"issue":"8","key":"2024020318572880000_jbmr2048-bib-0043","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1359\/JBMR.050317","article-title":"Asymptomatic vertebral deformity as a major risk factor for subsequent fractures and mortality: a long-term prospective study","volume":"20","author":"Pongchaiyakul","year":"2005","journal-title":"J Bone Miner Res."},{"issue":"11","key":"2024020318572880000_jbmr2048-bib-0044","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1001\/archinte.159.11.1215","article-title":"Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group","volume":"159","author":"Kado","year":"1999","journal-title":"Arch Intern Med."},{"issue":"11","key":"2024020318572880000_jbmr2048-bib-0045","doi-asserted-by":"crossref","first-page":"795","DOI":"10.7326\/0003-4819-150-11-200906020-00007","article-title":"Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures","volume":"150","author":"Cook","year":"2009","journal-title":"Ann Intern Med."},{"issue":"6","key":"2024020318572880000_jbmr2048-bib-0046","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/aje\/kws207","article-title":"Interpreting incremental value of markers added to risk prediction models","volume":"176","author":"Pencina","year":"2012","journal-title":"Am J Epidemiol."},{"issue":"2","key":"2024020318572880000_jbmr2048-bib-0047","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00198-010-1501-1","article-title":"Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards","volume":"22","author":"Vasikaran","year":"2011","journal-title":"Osteoporos Int."},{"issue":"11","key":"2024020318572880000_jbmr2048-bib-0048","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1002\/jbmr.467","article-title":"Urinary pentosidine improves risk classification using fracture risk assessment tools for postmenopausal women","volume":"26","author":"Tanaka","year":"2011","journal-title":"J Bone Miner Res."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0049","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00198-004-1689-z","article-title":"The impact of the use of multiple risk indicators for fracture on case-finding strategies: a mathematical approach","volume":"16","author":"De Laet","year":"2005","journal-title":"Osteoporos Int."},{"key":"2024020318572880000_jbmr2048-bib-0050","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1007\/s00198-011-1537-x","article-title":"Fracture risk prediction using FRAX: a 10-year follow-up survey of the Japanese Population-Based Osteoporosis (JPOS) Cohort Study","volume":"22","author":"Tamaki","year":"2012","journal-title":"Osteoporos Int."},{"issue":"1","key":"2024020318572880000_jbmr2048-bib-0051","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1359\/jbmr.070902","article-title":"Comparison of densitometric and radiographic vertebral fracture assessment using the algorithm-based qualitative (ABQ) method in postmenopausal women at low and high risk of fracture","volume":"23","author":"Ferrar","year":"2008","journal-title":"J Bone Miner Res."},{"issue":"3","key":"2024020318572880000_jbmr2048-bib-0052","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1359\/jbmr.2000.15.3.564","article-title":"Morphometric X-ray absorptiometry and morphometric radiography of the spine: a comparison of prevalent vertebral deformity identification","volume":"15","author":"Rea","year":"2000","journal-title":"J Bone Miner Res."}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbmr.2048","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/29\/2\/399\/56566309\/jbmr2048.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/29\/2\/399\/56566309\/jbmr2048.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T10:50:04Z","timestamp":1710327004000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/29\/2\/399-407\/7599018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,22]]},"references-count":52,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,7,22]]},"published-print":{"date-parts":[[2014,2,1]]}},"URL":"https:\/\/doi.org\/10.1002\/jbmr.2048","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2014,2,1]]},"published":{"date-parts":[[2013,7,22]]}}}