{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T23:28:29Z","timestamp":1772580509874,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T00:00:00Z","timestamp":1285286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We present the first report of the development of characteristic radiologic appearances of long bones during the first year of life in an infant with type V osteogenesis imperfecta (OI). We show the evolution of metaphyseal abnormalities from a rickets-like appearance to the classically described dense metaphyseal bands. These abnormalities suggest that the underlying defect in type V OI may involve a molecule common to both bone and cartilage that is involved in the regulation of growth plate development and metadiaphyseal ossification. Our findings provide new insights into skeletal development in type V OI and potentially yield useful clues to the identity of the defect underpinning the condition. \u00a9 2011 American Society for Bone and Mineral Research.<\/jats:p>","DOI":"10.1002\/jbmr.258","type":"journal-article","created":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T18:42:39Z","timestamp":1285353759000},"page":"894-898","source":"Crossref","is-referenced-by-count":27,"title":["Evolution of the radiographic appearance of the metaphyses over the first year of life in type V osteogenesis imperfecta: Clues to pathogenesis"],"prefix":"10.1093","volume":"26","author":[{"given":"Paul","family":"Arundel","sequence":"first","affiliation":[{"name":"Academic Unit of Child Health, University of Sheffield, and Sheffield Children's Hospital NHS Foundation Trust, Sheffield, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaka","family":"Offiah","sequence":"additional","affiliation":[{"name":"Academic Unit of Child Health, University of Sheffield, and Sheffield Children's Hospital NHS Foundation Trust, Sheffield, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J","family":"Bishop","sequence":"additional","affiliation":[{"name":"Academic Unit of Child Health, University of Sheffield, and Sheffield Children's Hospital NHS Foundation Trust, Sheffield, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,9,24]]},"reference":[{"key":"2024020318070291100_bib1","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1359\/jbmr.070418","article-title":"Natural history of hyperplastic callus formation in osteogenesis imperfecta type V","volume":"22","author":"Cheung","year":"2007","journal-title":"J Bone Miner 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